Clinical Evaluation of 2 Point-of-Care Lateral Flow Tests for the Diagnosis of Syphilis.

A diagnostic performance study comparing the only Food and Drug Administration-approved, point-of-care (POC) treponemal test (Syphilis Health Check) and the World Health Organization pre-qualified SD Bioline POC treponemal test against a treponemal hemagglutination test (TPHA) and a sequential algorithm of nontreponemal rapid plasma reagin and TPHA found both POC tests had >85% sensitivity compared with the TPHA and >85% sensitivity and >95% specificity compared with the rapid plasma reagin and TPHA standards.

Keywords

Adult, Algorithms, Antibodies, Bacterial, Cross-Sectional Studies, Female, Hemagglutination Tests, Humans, Male, Point-of-Care Systems, Reagins, Sensitivity and Specificity, Syphilis, Syphilis Serodiagnosis, Treponema pallidum, Young Adult

Journal Title

Sex Transm Dis

Journal ISSN

0148-5717
1537-4521

Volume Title

43

Publisher

Ovid Technologies (Wolters Kluwer Health)

Publisher DOI

https://doi.org/10.1097/OLQ.0000000000000498

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Scholarly Works - Institute of Public Health