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Characterizing the distinct structural changes associated with self‐reported knee injury among individuals with incident knee osteoarthritis: Data from the osteoarthritis initiative

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cam.issuedOnline2018-01-30
dc.contributor.authorDavis, Julie
dc.contributor.authorHarkey, Matthew
dc.contributor.authorWard, Robert
dc.contributor.authorMacKay, JW
dc.contributor.authorLu, Bing
dc.contributor.authorPrice, Lori
dc.contributor.authorEaton, Charles
dc.contributor.authorBarbe, Mary
dc.contributor.authorLo, Grace
dc.contributor.authorMcAlindon, Timothy
dc.contributor.authorDriban, Jeffrey
dc.contributor.orcidMacKay, James [0000-0001-7558-3800]
dc.date.accessioned2019-02-01T09:38:12Z
dc.date.available2019-02-01T09:38:12Z
dc.date.issued2018-04
dc.description.abstractWe aimed to characterize the agreement between distinct structural changes on magnetic resonance (MR) imaging and self‐reported injury in the 12 months leading to incident common or accelerated knee osteoarthritis (KOA). We conducted a descriptive study using data from baseline and the first 4 annual visits of the Osteoarthritis Initiative. Knees had no radiographic KOA at baseline (Kellgren‐Lawrence [KL]<2). We classified two groups: (1) accelerated KOA: a knee developed advanced‐stage KOA (KL = 3 or 4) within 48 months and (2) common KOA: a knee increased in radiographic severity (excluding those with accelerated KOA). Adults were 1:1 matched based on sex. The index visit was when a person met the accelerated or common KOA criteria. We limited our sample to people with MR images and self‐reported injury data at index visit and year prior. Among 226 people, we found fair agreement between self‐reported injuries and distinct structural changes (kappa = 0.24 to 0.31). Most distinct structural changes were medial meniscal pathology. No distinct structural changes (e.g., root or radial tears) appeared to differ between adults who reported or did not report an injury; except, all subchondral fractures occurred in adults who developed accelerated KOA and reported an injury. While there is fair agreement between self‐reported knee injuries and distinct structural changes, there is some discordance. Self‐reported injury may represent a different construct from distinct structural changes that occur after joint trauma. Clin. Anat. 31:330–334, 2018. © 2018 Wiley Periodicals, Inc.
dc.description.sponsorshipNational Institute of Arthritis and Musculoskeletal and Skin Diseases . Grant Number: R01‐AR065977
dc.identifier.doi10.17863/CAM.21707
dc.identifier.issn0897-3806
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/288665
dc.language.isoeng
dc.publisherWiley
dc.subject3208 Medical Physiology
dc.subject32 Biomedical and Clinical Sciences
dc.subject3202 Clinical Sciences
dc.subjectClinical Research
dc.subjectAging
dc.subjectArthritis
dc.subjectMusculoskeletal
dc.subjectInjuries and accidents
dc.subjectAged
dc.subjectFemale
dc.subjectHumans
dc.subjectKnee Injuries
dc.subjectMagnetic Resonance Imaging
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectOsteoarthritis, Knee
dc.titleCharacterizing the distinct structural changes associated with self‐reported knee injury among individuals with incident knee osteoarthritis: Data from the osteoarthritis initiative
dc.typeArticle
dcterms.dateAccepted2018-01-29
prism.endingPage334
prism.issueIdentifier3
prism.publicationNameClinical Anatomy
prism.startingPage330
prism.volume31
pubs.funder-project-idAddenbrooke's Charitable Trust (ACT) (24/15 A)
rioxxterms.licenseref.startdate2018-01-29
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review
rioxxterms.versionAM
rioxxterms.versionofrecord10.1002/ca.23054

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