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  • ItemPublished versionOpen Access
    Navigating freely-available software tools for metabolomics analysis
    (Springer Nature, 2017-09) Spicer, R; Salek, RM; Moreno, P; Cañueto, C; Steinbeck, C; Spicer, Rachel [0000-0002-2807-8796]
    Introduction The field of metabolomics has expanded greatly over the past two decades, both as an experimen- tal science with applications in many areas, as well as in regards to data standards and bioinformatics software tools. The diversity of experimental designs and instrumental technologies used for metabolomics has led to the need for distinct data analysis methods and the development of many software tools. Objectives To compile a comprehensive list of the most widely used freely available software and tools that are used primarily in metabolomics. Methods The most widely used tools were selected for inclusion in the review by either ≥ 50 citations on Web of Science (as of 08/09/16) or the use of the tool being reported in the recent Metabolomics Society survey. Tools were then categorised by the type of instrumental data (i.e. LC–MS, GC–MS or NMR) and the functionality (i.e. pre- and post- processing, statistical analysis, work ow and other func- tions) they are designed for. Results A comprehensive list of the most used tools was compiled. Each tool is discussed within the context of its application domain and in relation to comparable tools of the same domain. An extended list including additional tools is available at Tools which is classi ed and searchable via a simple con- trolled vocabulary. Conclusion This review presents the most widely used tools for metabolomics analysis, categorised based on their main functionality. As future work, we suggest a direct com- parison of tools’ abilities to perform specific data analysis tasks e.g. peak picking
  • ItemOpen Access
    Reflections and Lessons Learnt from an International Medical Camp in Kazakhstan
    (SciDoc Publishers, 2015-07-20) Nesaratnam, Nisha
    As a member of a team of 84 medical volunteers from the UK, USA, Canada and Russia, I travelled to Kazakhstan in August 2013 to take part in an international medical camp covering the town of Saran and nearby villages. Based in the Ophthalmology and Optometry clinics, I was able to gain a better understanding not only of ocular pathology, but also of the attributes needed for a successful medical camp. In this article, I reflect upon the role of the ophthalmologist, medical student and general volunteer in forming a shared collaboration with local doctors and patients, and consider lessons that can be implemented in daily clinical practice.