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Scholarly Works - Churchill College


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  • ItemOpen AccessAccepted version Peer-reviewed
    Assessing Socially Engaged Art
    (Wiley-Blackwell, 2018-12) Simoniti, V; Simoniti, Vid [0000-0001-5832-9587]
    The last twenty-five years have seen a radical shift in the work of politically committed artists. No longer content to merely represent social reality, a new generation of artists has sought to change it, blending art with activism, social regeneration projects, and even violent political action. I assess how this form of contemporary art should lead us to rethink theories of artistic value and argue that these works make a convincing case for an often-dismissed position, namely, the pragmatic view of artistic value. However, the pragmatic view, when properly applied, sets the bar high indeed—art that tries to change society should be considered good art only when it succeeds in making a tangible difference.
  • ItemOpen AccessPublished version Peer-reviewed
    A decade after the metabolomics standards initiative it's time for a revision.
    (Springer Science and Business Media LLC, 2017-09-26) Spicer, Rachel A; Salek, Reza; Steinbeck, Christoph; Spicer, Rachel A [0000-0002-2807-8796]; Salek, Reza [0000-0001-8604-1732]; Steinbeck, Christoph [0000-0001-6966-0814]
    A recent analysis of publicly available metabolomics data shows that the MSI guidelines are not well abided to in publicly shared metabolomics studies. We propose that the MSI guidelines should be revisited and revised, as has been done in other communities, to fit the current community needs.
  • ItemOpen AccessPublished version Peer-reviewed
    The future of metabolomics in ELIXIR.
    (F1000 Research Ltd, 2017) van Rijswijk, Merlijn; Beirnaert, Charlie; Caron, Christophe; Cascante, Marta; Dominguez, Victoria; Dunn, Warwick B; Ebbels, Timothy MD; Giacomoni, Franck; Gonzalez-Beltran, Alejandra; Hankemeier, Thomas; Haug, Kenneth; Izquierdo-Garcia, Jose L; Jimenez, Rafael C; Jourdan, Fabien; Kale, Namrata; Klapa, Maria I; Kohlbacher, Oliver; Koort, Kairi; Kultima, Kim; Le Corguillé, Gildas; Moreno, Pablo; Moschonas, Nicholas K; Neumann, Steffen; O'Donovan, Claire; Reczko, Martin; Rocca-Serra, Philippe; Rosato, Antonio; Salek, Reza M; Sansone, Susanna-Assunta; Satagopam, Venkata; Schober, Daniel; Shimmo, Ruth; Spicer, Rachel A; Spjuth, Ola; Thévenot, Etienne A; Viant, Mark R; Weber, Ralf JM; Willighagen, Egon L; Zanetti, Gianluigi; Steinbeck, Christoph; van Rijswijk, Merlijn [0000-0002-1067-7766]; Beirnaert, Charlie [0000-0003-3007-2569]; Gonzalez-Beltran, Alejandra [0000-0003-3499-8262]; Haug, Kenneth [0000-0003-3168-4145]; Jimenez, Rafael C [0000-0001-5404-7670]; Kale, Namrata [0000-0002-4255-8104]; Klapa, Maria I [0000-0002-2047-3185]; Moschonas, Nicholas K [0000-0002-2556-537X]; Rosato, Antonio [0000-0001-6172-0368]; Salek, Reza M [0000-0001-8604-1732]; Sansone, Susanna-Assunta [0000-0001-5306-5690]; Schober, Daniel [0000-0001-8014-6648]; Spicer, Rachel A [0000-0002-2807-8796]; Spjuth, Ola [0000-0002-8083-2864]; Thévenot, Etienne A [0000-0003-1019-4577]; Willighagen, Egon L [0000-0001-7542-0286]; Steinbeck, Christoph [0000-0001-6966-0814]
    Metabolomics, the youngest of the major omics technologies, is supported by an active community of researchers and infrastructure developers across Europe. To coordinate and focus efforts around infrastructure building for metabolomics within Europe, a workshop on the "Future of metabolomics in ELIXIR" was organised at Frankfurt Airport in Germany. This one-day strategic workshop involved representatives of ELIXIR Nodes, members of the PhenoMeNal consortium developing an e-infrastructure that supports workflow-based metabolomics analysis pipelines, and experts from the international metabolomics community. The workshop established metabolite identification as the critical area, where a maximal impact of computational metabolomics and data management on other fields could be achieved. In particular, the existing four ELIXIR Use Cases, where the metabolomics community - both industry and academia - would benefit most, and which could be exhaustively mapped onto the current five ELIXIR Platforms were discussed. This opinion article is a call for support for a new ELIXIR metabolomics Use Case, which aligns with and complements the existing and planned ELIXIR Platforms and Use Cases.
  • ItemOpen AccessPublished version Peer-reviewed
    Compliance with minimum information guidelines in public metabolomics repositories.
    (Springer Science and Business Media LLC, 2017-09-26) Spicer, Rachel A; Salek, Reza; Steinbeck, Christoph; Spicer, Rachel A [0000-0002-2807-8796]; Salek, Reza [0000-0001-8604-1732]; Steinbeck, Christoph [0000-0001-6966-0814]
    The Metabolomics Standards Initiative (MSI) guidelines were first published in 2007. These guidelines provided reporting standards for all stages of metabolomics analysis: experimental design, biological context, chemical analysis and data processing. Since 2012, a series of public metabolomics databases and repositories, which accept the deposition of metabolomic datasets, have arisen. In this study, the compliance of 399 public data sets, from four major metabolomics data repositories, to the biological context MSI reporting standards was evaluated. None of the reporting standards were complied with in every publicly available study, although adherence rates varied greatly, from 0 to 97%. The plant minimum reporting standards were the most complied with and the microbial and in vitro were the least. Our results indicate the need for reassessment and revision of the existing MSI reporting standards.