Department of Oncology
About this community
Sub-communities within this community
Collections in this community
(Elsevier, 2018-01-23)The controlled release of RNA polymerase II (RNAPII) from promoter-proximal pausing (PPP) sites is critical for transcription elongation in metazoans. We show that the human tumor suppressor BRCA2 interacts with RNAPII to ...
(Springer Nature, 2018-04)The endogenous metabolite itaconate has recently emerged as a regulator of macrophage function but the precise mechanism of action remains poorly understood. We report that itaconate is required for the activation of the ...