Theses - Chemistry
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Strategy for Controlled Protection of Redox-Cycling Ortho-Quinones with Self-Immolative Linkers
(2021-06-30)Natural product ortho-quinones have long shown potential as anticancer compounds, being the active components of traditional anticancer therapies from across the globe. Their ability to futile redox-cycle and cause an ... -
Transcriptomic studies of protein homeostasis perturbations in neurodegenerative disorders
Alzheimer’s Disease (AD) is the most common cause of dementia, but our understanding of its molecular origins is still incomplete. Genome-wide association studies (GWAS) have revealed key genes linked with the disease, but ... -
Design and Synthesis of Molecularly Encapsulated Conjugated Materials for Organic Electronics.
(2021-06-25)The (photo)physical properties of polymers are predominantly attributed to their intermolecular and intramolecular interactions. In conjugated polymers, charges or excitons can transport either along the conjugated backbone ... -
Effects of system complexity on protein aggregation in neurodegeneration
Alzheimer's disease (AD) is a neurodegenerative disorder, the leading cause of dementia worldwide, and is one of the most pressing challenges in ageing societies. The disease is characterised by extensive brain atrophy, ...
