Theses - Chemistry
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Understanding compound-induced histopathology in rat liver using gene expression network methods
Current drug discovery is a lengthy and costly pipeline; it takes between twelve and fifteen years and costs $1-2 billion (USD). As such, any compound failures represent a sunk cost – exacerbated if such failures occur ... -
C-H Activation of Functional Materials
(2020-01-01)This thesis comprises three projects on the theme of C-H activation for the synthesis of functional materials. Chapter 1 describes the development of gamma C-H carbonylation of free aliphatic secondary amines to form ... -
Bioinspired scattering materials: light transport in anisotropic, disordered systems
The study of light propagation in disordered media has attracted the interest of many researchers for its relevance to fundamental and applied problems, ranging from imaging through turbid media to the fabrication of white ... -
Iron nanoparticles and zirconium metal-organic frameworks for therapeutic application
This thesis reports experiments pertaining to the synthesis of magnetic nanoparticles (NPs) and metal-organic frameworks (MOFs) targeted at biomedical applications. Chapter 1 introduces the theoretical grounding for the ...
