Theses - Chemistry
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Studies within Fragment-Based Drug Discovery: Library Synthesis and Hit-to-Lead Optimisation
This thesis reports two projects aimed at addressing challenges within fragment-based drug discovery. The first project describes efforts towards utilising synthetic methodology to address deficiencies within fragment ... -
Understanding the Structure-Property Relationship in Diketopyrrolopyrroles for Organic Electronics
The effects of chain length, encapsulation and asymmetry of conjugated DPP-based polymers and small molecules were investigated. The first part of this thesis explored how chain length can affect the optical properties of ... -
Nuclear Magnetic Resonance Studies of Lithium Metal Anodes
(2020-12-14)Lithium metal has received a renewed interest as a promising anode material for next-generation, high-energy batteries owing to its high specific capacity (3860 mAh g-1) and low reduction potential (-3.04 V vs. the standard ... -
Investigating the role of protein aggregation in neurodegenerative diseases using super-resolution imaging
Neurodegenerative diseases, including Alzheimer's and Parkinson's diseases, are characterised by the progressive, irreversible loss of neuronal tissue accompanied by protein aggregation in the brain. Although identified ...
