Department of Medicine
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Reactive oxygen species and mitochondrial metabolism in acute myocardial ischaemia reperfusion injury: measurement and modulation
Reactive oxygen species (ROS) are known to play a central role in the pathology of acute myocardial infarction (AMI), where their production is driven by the metabolism of the citric acid cyclic intermediate succinate that ... -
Investigating the phenotype and function of tissue-resident B cells in mouse and human non-lymphoid organs
B lymphocytes play a central role in humoral immunity but also have antibody-independent functions. Studies to date have focused on B cells within blood and secondary lymphoid organs. This thesis sought to address the ... -
Bone morphogenetic proteins 9 & 10 in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a rare disease initiated by dysfunction of the pulmonary vascular endothelium. Mutations in BMPR2, which encodes the type-II bone morphogenic protein (BMP) receptor BMPR-II, explain ... -
Genomic surveillance of methicillin-resistant Staphylococcus aureus at local, regional and national levels
(2020-06-01)Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital-acquired infection, which is associated with increased cost and length of hospital stays and substantial morbidity and mortality. The rapid ...
