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A Potential Role for Exosomal TCTP Export in Vascular Remodeling in Pulmonary Arterial Hypertension. (American Thoracic Society, 2018-04-20)Pulmonary arterial hypertension (PAH) is characterized by increased proliferation and resistance to apoptosis of pulmonary vascular cells. Increased expression of translationally controlled tumor protein (TCTP), a pro-survival ...
Critical thresholds for intracranial pressure vary over time in non-craniectomised traumatic brain injury patients. (Springer Nature, 2018-07)Background: Intracranial pressure (ICP)- and cerebral perfusion pressure (CPP)- guided therapy is central to neurocritical care for traumatic brain injury (TBI) patients. We sought to identify time-dependent critical ...