Department of Medicine
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A zebrafish model to study the schistosome egg granuloma
Schistosomiasis is a disease caused by parasitic flatworms which reside within the venules of their human host. The disease pathology is caused by the eggs which they produce, and is primarily characterized by the granulomas ... -
Integrating -Omics For Studying Functional Role Of Ulcerative Colitis Risk Associated Loci.
Background: Ulcerative Colitis is chronic inflammatory condition of unknown etiology. Genome Wide Association Studies have successfully identified large number of UC risk associated loci, majority of which are located in ... -
Characterisation of the Apelin Receptor and its Endogenous Ligands, Apelin and Elabela/Toddler in the Cardio-Renal System
(2021-01-19)The apelin system is emerging as an important therapeutic target in several diseases. It comprises a G protein-coupled receptor, the apelin receptor, which binds two peptide ligands, namely apelin and Elabela/Toddler (ELA). ... -
Assessing Disease Modifying Therapies in Autosomal Dominant Polycystic Kidney Disease
(2020-10-27)Background: Vasopressin stimulates cyst growth in autosomal dominant polycystic kidney disease (ADPKD) and is a key therapeutic target. Evaluation of high water intake (HWI) as an alternative to pharmacological vasopressin ...
