Theses - Biochemistry
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Recent Submissions
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Phage host range and definition of genes implicated in Type III toxin-antitoxin-mediated abortive infection
(2019-04-27)Bacteria are under constant threat by their viral parasites, the bacteriophages (phages) and have evolved a range of anti-phage systems to defend themselves. One of these systems is termed abortive infection (Abi) where, ... -
Spatio-temporal properties of membrane-localized actin nucleating complexes
(2019-05-18)The actin cytoskeleton plays a vital role in various biological processes such as cell migration, morphogenesis, and intracellular trafficking. The polymerization of actin filaments at membranes provides the force for ... -
Development of a saposin A based native-like phospholipid bilayer system for NMR studies
(2019-04-30)Membrane proteins are important targets that represent more than 50% of current drug targets. However, characterisation of membrane proteins falls behind compared to their soluble counterparts. The most challenging part ... -
Structural and Biophysical Characterisation of Denatured States and Reversible Unfolding of Sensory Rhodopsin II
(2019-05-18)Our understanding of the folding of membrane proteins lags behind that of soluble proteins due to the challenges posed by the exposure of hydrophobic regions during in vitro chemical denaturation and refolding experiments. ...
