Theses - Biochemistry
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The Nucleosome Remodelling & Deacetylase complex: Genome folding & transcriptional regulation
Genome function is highly dependent on the three dimensional organisation of chromatin within a cell’s nucleus. Approximately 2 metres of DNA is folded to fit within a nucleus which is on the order of a few micrometers. ... -
Phosphorylation of The Smooth Muscle Master Splicing Regulator, RBPMS-A, Regulates its Splicing Activity
We have previously identified RBPMS as a master regulator of alternative splicing in differentiated smooth muscle cells (SMCs), responsible for controlling numerous components critical to differentiated SMC function ... -
Investigation of the regulatory interactions and dynamics between the circadian clock and sigma factors in the cyanobacterium Synechococcus elongatus
Circadian clocks are biological pacemakers that oscillate with a circa 24 h period. Many organisms across different taxa have evolved circadian clocks, which allow the anticipation of daily events caused by the Earth’s ... -
