Theses - Biochemistry
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Genome function is highly dependent on the three dimensional organisation of chromatin within a cell’s nucleus. Approximately 2 metres of DNA is folded to fit within a nucleus which is on the order of a few micrometers. ...
Phosphorylation of The Smooth Muscle Master Splicing Regulator, RBPMS-A, Regulates its Splicing Activity We have previously identified RBPMS as a master regulator of alternative splicing in differentiated smooth muscle cells (SMCs), responsible for controlling numerous components critical to differentiated SMC function ...
Investigation of the regulatory interactions and dynamics between the circadian clock and sigma factors in the cyanobacterium Synechococcus elongatus Circadian clocks are biological pacemakers that oscillate with a circa 24 h period. Many organisms across different taxa have evolved circadian clocks, which allow the anticipation of daily events caused by the Earth’s ...