Theses - Medicine
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Study of the Phenotypic Characteristics and Genetic Risk Factors of Primary Sclerosing Cholangitis
(2019-10-01)Primary sclerosing cholangitis (PSC) is a progressive chronic cholestatic liver disease, affecting young males predominantly. It causes stricturing of the intrahepatic and extrahepatic bile ducts, often leading to biliary ... -
Mechanistic Analysis and Optimisation of Nipple Shield Drug Delivery Devices
(2019-07-19)The work in this dissertation focused on delivering a nipple shield drug delivery device that is ready for clinical trials with the hope of making a positive impact on the health of neonates, infants, and paediatrics five ... -
Incidence of Steal Phenomena and Steal Syndrome in Patients with Arteriovenous Fistulae
(2019-06-13)SUMMARY This thesis aims to examine three key questions: 1. Can digital finger pressure measurements and the derivative digital brachial pressure index help to identify patients at risk of arteriovenous access ... -
The Cardiovascular Effect of GLP-1 in Humans
(2019-07-20)The incretin glucagon-like peptide-1 (GLP-1) abolishes post-ischemic left ventricular contractility (stunning) in humans but the mechanism remains elusive. I hypothesized that this effect is mediated by peripheral or ...
