Theses - Medicine
About this collection
Recent Submissions
-
Proteomic Investigation of Interferon Alpha Stimulation and Viral Regulation to Identify Candidate Antiviral Restriction Factors
Antiviral restriction factors (ARFs) are host proteins that play key roles in inhibiting viral infection. The plasma membrane provides a critical interface between the cell and the virus, meaning that proteins present here ... -
Developing frameworks to measure physical activity in free-living populations in sub-Saharan Africa
(2020-06-30)Background and objectives: Sub-Saharan Africa (SSA) has an increasing burden of noncommunicable diseases (NCDs). Comprehensive and context-specific evidence on the major modifiable risk factors for NCDs, such as physical ... -
A genome-wide association study in chronic thromboembolic pulmonary hypertension and the ADAMTS13-VWF axis
Chronic thromboembolic pulmonary hypertension (CTEPH) is an important and severe consequence of pulmonary embolism (PE), resulting from failure of thrombus resolution. Identifying genetic risk factors for CTEPH would provide ... -
Imaging innate immune cell behaviour in lymphoid organs
Innate immune cells generate the early host response to infection and tissue injury. Neutrophils are rapidly recruited from circulation to inflammatory tissues for pathogen killing. Type 2 innate lymphoid cells (ILC2s) ...
