Theses - Medicine
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Recent Submissions
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The role of glycosaminoglycans in vascular stiffness and non-osmotic sodium storage
(2018-07-21)The goal of this thesis was to investigate the interplay between sodium, glycosaminoglycans, vascular stiffness, and hypertension. In contrast to the traditional view of salt-dependent hypertension, recent studies have ... -
Understanding functional mechanisms of genetic susceptibility to mycobacterial infection
(2018-07-21)Tuberculosis remains a major public health problem and one of the leading causes of death worldwide. Human genetic factors determine susceptibility to M. tuberculosis (M. tb) infection and predispose to clinical TB. ... -
Experimental Modelling and Molecular Mechanisms of Wallerian Degeneration in Traumatic Axonal Injury
(2018-07-21)Traumatic brain injury (TBI) is a common event that can lead to profound consequences for the individual involved, and a considerable socio-economic cost. The initial injury event triggers a series of secondary brain injury ... -
Large Artery Stiffness: Genes and Pathways
(2018-07-20)Aortic stiffness underlies systolic hypertension, promotes heart failure and is associated with in- creased cardiovascular morbidity and mortality. It is regarded as a primary driver of left ventricular hypertrophy and ...
