Theses - Medicine
About this collection
Recent Submissions
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Identification and characterisation of Group 3 Innate Lymphoid Cells in the renal tract
(2019-10-08)Innate lymphoid cells (ILCs) bear similarities to T-helper (Th) cells, but lack T cell receptors. The three groups mirror the effector functions of Th1, Th2 and Th17 cells and share the same transcription factors and ... -
Study of the intracellular trafficking of the pre-T-cell receptor and its role in T-cell lineage commitment
(2019-11-30)T-cell development is a complex multi-step process, driving the maturation of hematopoietic stem cells into fully functional mature T-cells that play a major role in the adaptive immune response against pathogens. This ... -
Association of cardiovascular and musculoskeletal biomarkers with clinical outcomes in chronic obstructive pulmonary disease.
(2019-10-26)Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in the world. In addition to premature mortality, the consequent socio-economic burden is high, causing reduced quality of life, loss of ... -
Study of the Phenotypic Characteristics and Genetic Risk Factors of Primary Sclerosing Cholangitis
(2019-10-01)Primary sclerosing cholangitis (PSC) is a progressive chronic cholestatic liver disease, affecting young males predominantly. It causes stricturing of the intrahepatic and extrahepatic bile ducts, often leading to biliary ...
