Theses - Medicine
About this collection
Recent Submissions
-
THE EXPLORATION OF THE VALIDITY OF QUANTITATIVE 2-DEOXY-2-[FLUORINE-18] FLUORO-D-GLUCOSE (18F-FDG) POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY (PET/CT) TO ASSESS LUNG INFLAMMATION
Lung diseases are one of the leading causes of death in the UK; responsible for 20% of all deaths each year. Inflammation is thought to be an important driver of the pathogenesis and progression of several lung diseases. ... -
Radiomics and Machine Learning in the Prediction of Cardiovascular Disease
Carotid atherosclerosis is a major risk factor for ischaemic stroke which is a leading cause of death worldwide. For stroke survivors, 1 in 4 will have another stroke within five years. Carotid CT angiography (CTA) is ... -
From Phenotype to Genotype: Discovery of New Molecular Primary Immunodeficiencies
Since the 1950s, the investigation of genetic causes of primary immunodeficiencies has fundamentally shaped our understanding of the immune system, and that fountain of knowledge has continued to expand explosively as we ... -
T Helper Cell Dysfunction in ANCA Associated Vasculitis
Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is an autoimmune disease characterised by inflammation of small blood vessels that leads to organ dysfunction. Auto-reactive B cells produce pathogenic ...
