Theses - Zoology
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Identifying a common cause of the loser cell status in Drosophila melanogaster.
(2019-03-31)Cell competition is the process whereby less fit cells termed “losers” are selectively eliminated from a tissue by their fitter neighbors – or “ winners.” This sacrifice of aberrant cells is thought to have evolved at the ... -
The mechanisms underlying mechanical cell competition and leader cell migration in mammalian epithelia
Cell competition is a form of cell-cell signalling that results in the elimination of less fit cells from a tissue by their fitter counterparts. I take advantage of an established in vitro model of cell competition using ... -
Investigating the calcium wave and actin dynamics at Drosophila egg activation
(2019-03-23)Egg activation is a series of highly coordinated processes that prepare the mature oocyte for embryogenesis. Typically associated with fertilisation, egg activation results in the resumption of the cell cycle, expression ... -
Using new tools to study the neural mechanisms of sensation: Auditory processing in locusts and translational motion vision in flies
(2019-04-27)This thesis describes work from both the University of Cambridge in the lab of Berthold Hedwig and from the HHMI Janelia Research Campus in the lab of Michael Reiser. At the University of Cambridge, my work involved the ...
