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Undertakes innovative biomedical research to discover the molecular mechanisms that underlie normal cellular processes and functions, and how, over lifetime, their failure or abnormality may lead to disease
The Babraham Institute is located six miles south-east of the university city of Cambridge, UK. We undertake innovative biomedical research to discover the molecular mechanisms that underlie normal cellular processes and functions, and how, over lifetime, their failure or abnormality may lead to disease. The Institute is a registered charity, sponsored by the Biotechnology and Biological Sciences Research Council (BBSRC), to underpin its national responsibilities for healthcare research and training.
Our research is also supported by the Medical Research Council (MRC) and many medical charities and other organisations.
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(2020-07-17)Protein post-translational modifications (PTMs) are an essential and conserved mechanism that allows eukaryotic cells to coordinate rapid responses to changing environmental conditions. Protein kinases, comprising a large ...
(2020-05-16)Investigation of mTOR-independent regulation of macroautophagy Richard Ian Odle Macroautophagy is a critical catabolic response to cellular stress, enabling lysosomal mediated breakdown of cytosolic cargo. The ...
Global alterations of the epigenetic landscape define endometrial receptivity and provide a hallmark for endometriosis (2020-05-16)The endometrium plays an essential role in the female reproductive cycle. It undergoes extensive morphological and transcriptional changes during the menstrual cycle, in response to steroid hormones. For implantation to ...
Microbiota regulate short chain fatty acids and influence histone acylations in intestinal epithelial cells. (2020-05-12)The intestinal microbiota have a vital role in aiding digestion by metabolising dietary fibres. In this process, they produce short chain fatty acids (SCFAs) such as butyrate, an important energy source for intestinal ...