Babraham Institute
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Undertakes innovative biomedical research to discover the molecular mechanisms that underlie normal cellular processes and functions, and how, over lifetime, their failure or abnormality may lead to disease
The Babraham Institute is located six miles south-east of the university city of Cambridge, UK. We undertake innovative biomedical research to discover the molecular mechanisms that underlie normal cellular processes and functions, and how, over lifetime, their failure or abnormality may lead to disease. The Institute is a registered charity, sponsored by the Biotechnology and Biological Sciences Research Council (BBSRC), to underpin its national responsibilities for healthcare research and training.
Our research is also supported by the Medical Research Council (MRC) and many medical charities and other organisations.
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The RNA-Binding protein PTBP1 plays a role in the activation of mouse CD8 T cells
CD8 T cells play a pivotal role in immune responses against intracellular pathogens, including viruses and bacteria, and in tumour surveillance. After encountering an antigen, CD8 T cells undergo cell growth, clonal ... -
Elucidating the effects of dietary change on replicative ageing in Saccharomyces cerevisiae
Saccharomyces cerevisiae, baker's yeast, is an established model organism of ageing research. There are many different pathologies associated with the ageing of yeast, ranging from phenotypic to global transcriptome changes. ... -
Role of Histone Lysine Demethylase, KDM1B, in Trophoblast Stem Cell Self-Renewal and Differentiation
The first cell fate decision in development occurs at the blastocyst stage with the emergence of the trophectoderm (TE) and the inner cell mass (ICM). The TE is the precursor population of all major placental cell types. ... -
Investigation of the three dimensional organisation of the genome in B cell development
In order to detect and eliminate a myriad of different antigens, the adaptive immune systems of jawed vertebrates have evolved to generate diverse repertoires of antigen receptors (AgRs). AgR diversity is primarily generated ...
