Department of Pathology
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MicroRNAs and Extracellular Vesicles: investigating their role in the Testicular Germ Cell Tumour Microenvironment. Testicular germ cell tumours (TGCT) are the most common malignancy in young adult men and are characterised by their broad heterogeneity in terms of differentiation stage, histological presentation and capacity for ...
Studying the Transcriptional and Epigenetic Perturbations of Haematopathologies Expressing NPM1-ALK Anaplastic lymphoma kinase (ALK) is a tyrosine kinase involved in the development of the gut and nervous system, initially cloned from cases of T-cell lymphoma. ALK has been frequently implicated in diverse cancers through ...
Studying lung development in vitro: expanding the genetic toolbox and analysis of SOX2 and SOX9 function Respiratory disease is a growing threat to human health worldwide. Induced pluripotent stem cell (iPSC) based stem cell therapy is promising for end-stage respiratory disease patients. Generation of mature/functional lung ...