Theses - Pathology
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Recent Submissions
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An exploration of the interplay between HSV-1 and the non-homologous end joining proteins PAXX and DNA-PKcs
(2019-01-30)DNA damage response (DDR) pathways are essential in maintaining genomic integrity in cells, but many DDR proteins have other important functions such as in the innate immune sensing of cytoplasmic DNA. Some DDR proteins ... -
Using a Porcine Maternal Infanticide Model to Investigate the Inheritance of Human Puerperal Psychosis
(2019-05-18)Puerperal Psychosis is the most severe form of postnatal psychiatric illness, and is a psychiatric emergency. Human-based research to find a means of genetically predicting a woman’s risk of puerperal psychosis has so far ... -
Characterisation of a novel leukocyte receptor complex-encoded receptor TARM1
(2018-10-20)Cellular immune responses are orchestrated by an intricate balance of activating and inhibitory signals transmitted by cell surface receptors. Perturbations in this balance by overamplified or dysregulated signalling ... -
The Role of FBXO7 in Mitochondrial Biology and Parkinson's Disease
(2018-10-20)Parkinson’s disease is a progressive neurodegenerative disorder of the central nervous system, manifesting with both motor and non-motor symptoms. Autosomal recessive mutations in the FBXO7 gene have been identified to ...
