Theses - Pathology
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Human antibody-mediated immunity against infection and parasite fecundity in Schistosoma mansoni and Schistosoma haematobium infection
Through a combination of epidemiological and proteomic methods, the aim of this thesis was to advance understanding of antibody-driven immune responses that partially protect against infection and reduce fecundity in human ... -
Targeting oncogenic microRNAs in malignant germ cell tumours.
(2021-07-17)Malignant germ cell tumours (mGCTs) are a heterogenous group of tumours that occur primarily in the testes and ovaries but also in other anatomical sites, and affect people of all ages. It was established by the Coleman ... -
MicroRNAs and Extracellular Vesicles: investigating their role in the Testicular Germ Cell Tumour Microenvironment.
Testicular germ cell tumours (TGCT) are the most common malignancy in young adult men and are characterised by their broad heterogeneity in terms of differentiation stage, histological presentation and capacity for ... -
Studying the Transcriptional and Epigenetic Perturbations of Haematopathologies Expressing NPM1-ALK
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase involved in the development of the gut and nervous system, initially cloned from cases of T-cell lymphoma. ALK has been frequently implicated in diverse cancers through ...
