Theses - Pathology
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The Role of Cervical Reserve Cells in Epithelial Regeneration and Homeostasis in the Murine and Human Cervix
(2022-01-01)How cervical epithelium maintains homeostasis and repair, and how the high-risk human papilloma viruses (HR-HPV) drive neoplasia at the cervical transformation zone (TZ) has been poorly researched. The cervical TZ is thought ... -
Development and Implementation of a Cervical Patch Sampling Approach for Cervical Screening and the Study of HPV Transmission
HPV is the causative agent behind 99.7% of Cervical cancers and is implicated in the pathogenesis of many other tumours such as Anal and Oropharyngeal tumours. Recently some studies have called into question the suitability ... -
Profiling the Acquisition and Diversity of Antibodies to Human Norovirus in Infants
Human norovirus (HNV) is considered the most common cause of viral gastroenteritis worldwide, yet there is a deficit in our understanding of protective immunity against HNV. Such information is critical to vaccines currently ... -
Human antibody-mediated immunity against infection and parasite fecundity in Schistosoma mansoni and Schistosoma haematobium infection
Through a combination of epidemiological and proteomic methods, the aim of this thesis was to advance understanding of antibody-driven immune responses that partially protect against infection and reduce fecundity in human ...
