Theses - Pathology
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Recent Submissions
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Bacterial Manipulation of Actin Dynamics via p21 Activated Kinases and Cofilin
The actin cytoskeleton is a complex and dynamic network of protein filaments involved in a great number of cellular processes essential for cellular homeostasis and survival. The dynamic nature of the cytoskeleton requires ... -
Investigating Early Lesion Formation Following Papillomavirus Infection Using a Mouse Model and Cell Culture
(2020-03-03)Papillomaviruses (PV) are small non-enveloped double-stranded DNA tumour viruses, which are able to infect more than 80 different host species. They are a diverse group with over 400 types discovered, of which almost half ... -
Effects of Oncostatin-M Receptor overexpression on cervical squamous cell carcinoma cells and their extracellular vesicles
(2020-04-21)Cervical carcinoma remains the fourth most common cause of cancer in women worldwide. Cytological screening and introduction of prophylactic HPV vaccines have drastically decreased incidence rates in high income countries. ... -
Functional Analysis of the F-box protein Fbxl17
(2020-04-29)Advances in DNA sequencing technology have allowed detailed characterisation of cancer genomes and has highlighted the contribution of somatic structural variations to the mutational landscape of epithelial tumours. However, ...
