Medical Research Council and Wellcome Trust
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Statistical models for estimating the intake of nutrients and foods from complex survey data
(2019-03-02)Background: The consequences of poor nutrition are well known and of wide concern. Governments and public health agencies utilise food and diet surveillance data to make decisions that lead to improvements in nutrition. ... -
Functional analysis of Shigella encoded IpaH E3 ubiquitin ligases in cell-autonomous immunity
Shigella flexneri is a highly adapted pathogen that invades the host cytosol and causes bacillary dysentery. Shigella has evolved powerful countermeasures to disarm host defense mechanisms; amongst them a family of twelve ... -
STUDIES IN OOCYTES FROM THREE MAMMALIAN SPECIES DEMONSTRATE THAT MEIOTIC KINETOCHORES ARE COMPOSED OF PREVIOUSLY UNIDENTIFIED SUBDOMAINS AND REVEAL TWO NOVEL MECHANISMS BEHIND THE MATERNAL-AGE EFFECT IN HUMANS
(2020-06-14)Poor egg quality is the leading cause of pregnancy loss and Down’s syndrome. While even eggs in young women frequently contain an incorrect number of chromosomes and are therefore unlikely to give rise to a viable pregnancy, ... -
Protein Shape Description and its Application to Shape Comparison
(2018-11-24)There are currently over 138, 000 known macromolecular structures deposited in the wwPDB (Worldwide Protein Data Bank) database. While all the macromolecular structure files contain information about a particular structure, ...
