Department of Veterinary Medicine
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Origin, evolution, and global spread of a transmissible cancer clone
(2019-10-26)Clonally transmissible cancers are malignant cellular clones that spread between unrelated individuals by the physical transfer of living cancer cells. These clones can ‘metastasise’ through populations, having adapted to ... -
A tool of "barcoded viruses" to study influenza virus transmission dynamics
(2019-08-01)The aim of this study was to establish a novel version of powerful “barcode viruses” as a tool for studying the replication and transmission dynamics of influenza virus in vitro and in vivo. Five barcoded APR8 viruses were ... -
Barcoded Transposon Directed Insertion-site Sequencing (TraDIS); a tool to improve our understanding of the functional genomics of Streptococcus equi subsp. equi
(2019-07-20)Strangles, caused by Streptococcus equi (S. equi) remains the most frequently diagnosed infectious disease of horses and is a cause of significant welfare and economic cost. Vaccine research has been limited by the time ... -
Study of the Immune Correlates of Protection in Rhesus Macaques Vaccinated against Simian Immunodeficiency Virus
(2019-07-19)After more than thirty years since the Human Immunodeficiency Virus (HIV) was identified, only the RV144 phase III vaccine clinical trial provided evidence of protection from virus infection, with 31.2% of the patients ...
