European Bioinformatics Institute (EMBL-EBI)
Recent Submissions
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On the epigenetic ageing clock in humans
(2019-11-30)Epigenetic clocks are mathematical models that predict the biological age of an organism using DNA methylation data, and which have emerged in the last few years as the most accurate biomarkers of the ageing process. ... -
Leveraging genomic and molecular variations to understand the regulatory landscape in human cancers and differentiating stem cells
(2019-10-26)Genetic and molecular variations are closely intertwined; while genetic factors drive phenotypic differences ranging from gene expression to organismal traits, phenotypic variations are the target of evolutionary selection, ... -
Assessing the usage of alternative transcripts in human tissues from RNA-seq and proteomics data
(2019-10-26)Alternative splicing is an important step in gene expression regulation in eukaryotes, through which a single gene can express different transcript isoforms. We can now use RNA sequencing (RNA-seq) data to identify which ... -
Quantifying expression variability in single-cell RNA sequencing data
(2019-07-19)Transcriptional noise is an intrinsic feature of cell populations and plays a driving role in mammalian development, tissue homoeostasis and immune function. While expression heterogeneity, a phenotypic readout of ...
