European Bioinformatics Institute (EMBL-EBI)
Recent Submissions
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Computational studies on ageing and age-related diseases
Age is the major risk factor for a variety of non-communicable diseases. As life expectancy increases, ageing poses significant challenges to the individual, society, and healthcare systems. Ageing is a complex process ... -
The Influence of Structural Constraints on Protein Evolution
Few mathematical models of sequence evolution incorporate parameters describingprotein structure, despite its high conservation, essential functional role and the increasingavailability of structural data. The primary goal ... -
Statistical methods to infer kinase activities and kinase-substrate interactions using phosphoproteomic data
(2020-07-17)The activity of kinases play an important role during cell signalling. They phosphorylate proteins to regulate their interactions, structural conformation, cell location and enzymatic activation. Mass Spectrometry (MS) ... -
Computational Analysis of Transcriptional Regulation
(2020-01-17)It is doubtful Friedrich Miescher appreciated how groundbreaking and transformative his isolation of ’nuclein’ in 1869 would prove. Eukaryotic gene expression is a noisy process that is subject to multiple layers of ...
