European Bioinformatics Institute (EMBL-EBI)
Recent Submissions
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DNA Phonology: Investigating the Codon Space
(2003-11-04)The main part of the thesis is concerned with large-scale studies of codon usage in completely sequenced genomes. A new compositional analysis scheme is presented, complete with a number of computation and visualisation ... -
Insights into transcriptional regulation from natural and induced variation in closely related species
Despite years of research, numerous aspects of gene regulatory mechanisms and their contributions to shaping phenotypic characteristics remain elusive. In this thesis, I gain insights into mechanisms of transcriptional ... -
Computational discovery and modelling of tandem domain repeats in proteins
(2021-06-10)Domains are functional and evolutionary units of proteins that typically fold into stable globular structures. A small subset of natural multidomain proteins contain large arrays of nearly identical domains repeated in ... -
Investigating normal human gene expression in tissues with high-throughput transcriptomic and proteomic data.
With the improvement of high-throughput technologies during the last decade, several studies exploring the normal gene expression in human tissues have been published. Many studies examine the transcriptome with RNA ...
