European Bioinformatics Institute (EMBL-EBI)
Recent Submissions
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Statistical methods to infer kinase activities and kinase-substrate interactions using phosphoproteomic data
(2020-07-17)The activity of kinases play an important role during cell signalling. They phosphorylate proteins to regulate their interactions, structural conformation, cell location and enzymatic activation. Mass Spectrometry (MS) ... -
Computational Analysis of Transcriptional Regulation
(2020-01-17)It is doubtful Friedrich Miescher appreciated how groundbreaking and transformative his isolation of ’nuclein’ in 1869 would prove. Eukaryotic gene expression is a noisy process that is subject to multiple layers of ... -
Quantifying the pro- and antimutagenic roles of DNA damage and repair
(2020-07-25)Genome integrity is essential to the survival of any living organism. The genome is constantly challenged by a multitude of endogenous and exogenous mutagenic factors such as environmental exposures or replication errors. ... -
Structural analysis of phosphorylation hotspots and kinase target preferences.
(2019-12-11)Cells are constantly sensing and adapting to changes in conditions. Protein post-translational regulation is one of the fastest mechanism used by cells to relay signals from sensors to effectors during such adaptations. ...
