Theses - EMBL-EBI
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Recent Submissions
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A genetic analysis of molecular traits in skeletal muscle
(2018-04-28)Genome Wide Association Studies (GWASs) have identified variants associated with disease that promise to deliver insights into disease aetiology. However, because many GWAS variants lie in non-coding genomic regions, it ... -
Elucidating the function and biogenesis of small non-coding RNAs using novel computational methods & machine learning.
(2017-10-31)The discovery of RNA in 1868 by Friedrich Miescher was meant to be the prologue to an exciting new era in Biology full of scientific breakthroughs and accomplishments. Since then, RNAs have been proven to play an indispensable ... -
Elucidating the mechanistic impact of single nucleotide variants in model organisms
(2018-02-06)Understanding how genetic variation propagate to differences in phenotypes in individuals is an ongoing challenge in genetics. Genome-wide association studies have allowed for the identification of many trait-associated ... -
The evolution, modifications and interactions of proteins and RNAs
(2017-12-01)Proteins and RNAs are two of the most versatile macromolecules that carry out almost all functions within living organisms. In this thesis I have explored evolutionary and regulatory aspects of proteins and RNAs by studying ...
