Theses - EMBL-EBI
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Recent Submissions
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Assessing the usage of alternative transcripts in human tissues from RNA-seq and proteomics data
(2019-10-26)Alternative splicing is an important step in gene expression regulation in eukaryotes, through which a single gene can express different transcript isoforms. We can now use RNA sequencing (RNA-seq) data to identify which ... -
Quantifying expression variability in single-cell RNA sequencing data
(2019-07-19)Transcriptional noise is an intrinsic feature of cell populations and plays a driving role in mammalian development, tissue homoeostasis and immune function. While expression heterogeneity, a phenotypic readout of ... -
The evolution of protein kinase specificity
(2019-04-27)Protein phosphorylation represents one of the most important post-translational modifica- tions (PTMs) for cell signalling, and is is catalysed by a group of enzymes called protein kinases. Through this activity they serve ... -
Statistical Methods for the Analysis of Contextual Gene Expression Data
(2019-02-05)Technological advances have enabled profiling gene expression variability, both at the RNA and the protein level, with ever increasing throughput. In addition, miniaturisation has enabled quantifying gene expression from ...
