Theses - EMBL-EBI
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Recent Submissions
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Investigating normal human gene expression in tissues with high-throughput transcriptomic and proteomic data.
With the improvement of high-throughput technologies during the last decade, several studies exploring the normal gene expression in human tissues have been published. Many studies examine the transcriptome with RNA ... -
Understanding the genetics and function of complex human retinal phenotypes
The human retina is the tissue at the back of the eye responsible for converting light stimulus into neuronal signal that can be interpreted by the brain. To perform this integral role within the central nervous system, ... -
Using single-cell RNA-seq to assess the effect of common genetic variants on gene expression during development
Over the last fifteen years, genome-wide association studies (GWAS) have been used to identify thousands of DNA variants associated with complex traits and diseases, by exploiting naturally occurring genetic variation in ... -
Mapping the Genomic Context of Mutagenesis
(2020-11-30)The accumulation of genomic mutations leads to the formation of cancer. For this reason, many efforts have been undertaken to characterise mutational processes in terms of their genomic imprints. A particularly successful ...
