Department of Physiology, Development and Neuroscience
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The role of cell body density in ruminant retina mechanics assessed by atomic force and Brillouin microscopy
Cells in the central nervous system (CNS) respond to the stiffness of their environment. CNS tissue is mechanically highly heterogeneous, thus providing motile cells with region-specific mechanical signals. While CNS ... -
Undergraduate students as co-producers in the creation of first-year practical class resources
Undergraduate students are increasingly working with academic staff to evaluate and design teaching materials in Higher Education, thereby moving from being passive consumers of knowledge to genuine partners in their ... -
Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum
(Cell Press, 2017-06-06)Embryonic stem cells (ESC) are characterised by the pluripotent capacity to generate all embryonic lineages. Here we show ESC can occupy a spectrum of distinct transcriptional and epigenetic states in response to varied ... -
Talin - the master of integrin adhesions
(The Company of Biologists Ltd, 2017-08-01)Talin has emerged as the key cytoplasmic protein that mediates integrin adhesion to the extracellular matrix. In this Review, we draw on experiments performed in mammalian cells in culture and Drosophila to present evidence ...
