Theses - Physiology, Development and Neuroscience
About this collection
Recent Submissions
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Revealing Preferences: a neuroeconometric approach to understanding decision-making behaviour
(2019-07-01)Rewards represent probably the most important objects for our life. Rewards are external items that an individual identifies as optimal to satisfy internal needs. Optimal rewards are associated with so-called ‘high reward ... -
Investigating the Epigenetic Mechanism Behind Transgenerational Inheritance in Mice with Abnormal Folate Metabolism
(2019-05-18)Exposure to environmental stressors can impact our health and that of future generations even when they are not similarly exposed. How disease risk is inherited is unclear. My thesis focuses on a mouse model of transgenerational ... -
CARDIAC ENERGY METABOLISM IN ISCHAEMIA AND TYPE 1 DIABETES
(2019-07-16)Ischaemic heart disease represents a restriction of blood, and therefore oxygen, supply to the myocardium. This leads to a remodelling of cardiac metabolism, which can exacerbate production of damaging reactive oxygen ... -
Transcription and chromatin dynamics in the Notch signalling response
(2019-05-18)During normal development, different genes are expressed in different cell types, often directed by cell signalling pathways and the pre-existing chromatin environment. The highly-conserved Notch signalling pathway is ...
