About this community

Sub-communities within this community

Collections in this community

Recent Submissions

  • Regulation of IP3 receptors by cyclic AMP. 

    Taylor, Colin W (Elsevier, 2016-11-06)
    Ca$^{2+}$ and cAMP are ubiquitous intracellular messengers and interactions between them are commonplace. Here the effects of cAMP on inositol 1,4,5-trisphosphate receptors (IP$_{3}$Rs) are briefly reviewed. All three ...
  • Structural and functional landscape of MFS and MATE efflux pumps 

    Nair, AV; Lee, KW; van Veen, HW (Springer, 2016)
    Multidrug transporters play a crucial role in causing drug resistance in infectious microorganisms and tumors. They are integral membrane proteins that exhibit an exceptionally broad specificity for unrelated molecules ...
  • Bacterial ABC multidrug exporters: from shared proteins motifs and features to diversity in molecular mechanisms. 

    Van Veen, HW (Springer, 2016)
    Bacterial ATP-binding cassette (ABC) exporters embrace an enormous range of biological processes. They can mediate the efflux of a wide variety of substrate ranging from small inorganic ions, drugs and antibiotics to large ...
  • Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity 

    Wetzel, C; Pifferi, S; Picci, C; Gök, C; Hoffmann, D; Bali, KK; Lampe, A et al. (Nature Publishing Group, 2016-12-12)
    The skin is equipped with specialized mechanoreceptors that allow the perception of the slightest brush. Indeed, some mechanoreceptors can detect even nanometer-scale movements. Movement is transformed into electrical ...

View more