Department of Pharmacology
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Tandem-repeat (TR) domains occur in approximately one third of all proteins, yet these domains are less well understood compared with their globular counterparts. TR proteins act as molecular scaffolds that facilitate ...
THE USE OF CATALYTICALLY DEAD CAS9 TO IDENTFY KEY TRANSCRIPTION REGULATORS IN TRIPLE NEGATIVE BREAST CANCER Triple-negative breast cancer (TNBC) accounts for approximately 15-20% of all breast cancer cases. It tends to be aggressive, high-grade and poorly differentiated tumour with poor clinical outcome. Lack of expression of ...