Department of Pharmacology
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The aim of this body of work has been to further understanding of the signalling and functional properties of a unique family of cell surface receptors known as G protein-coupled receptors (GPCRs), and one of their subclasses: ...
Type 2 diabetes mellitus (T2DM) is characterised by the hormonal imbalance of insulin and glucagon, leading to dysfunctional glucose homeostasis. Glucagon-like peptide 1 (GLP-1), which is an incretin hormone, activates the ...
Tandem-repeat (TR) domains occur in approximately one third of all proteins, yet these domains are less well understood compared with their globular counterparts. TR proteins act as molecular scaffolds that facilitate ...