About this community

Sub-communities within this community

Collections in this community

Recent Submissions

  • Ca2+ signals initiate at immobile IP3 receptors adjacent to ER-plasma membrane junctions. 

    Thillaiappan, Nagendra Babu; Chavda, Alap P; Tovey, Stephen C; Prole, David Lawrence; Taylor, Colin William (Springer Nature, 2017-11-15)
    IP3 receptors (IP3Rs) release Ca2+ from the ER when they bind IP3 and Ca2+. The spatial organization of IP3Rs determines both the propagation of Ca2+ signals between IP3Rs and the selective regulation of cellular responses. ...
  • Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing. 

    Bach, Karsten; Pensa, Sara; Grzelak, Marta; Hadfield, James; Adams, David J; Marioni, John Carlo; Khaled, Walid Taha (Springer Nature, 2017-12-11)
    The mammary gland is a unique organ as it undergoes most of its development during puberty and adulthood. Characterising the hierarchy of the various mammary epithelial cells and how they are regulated in response to ...
  • Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein. 

    Al-Ramahi, Ismael; Panapakkam Giridharan, Sai Srinivas; Chen, Yu-Chi; Patnaik, Samarjit; Safren, Nathaniel; Hasegawa, Junya; de Haro, Maria et al. (2017-12-26)
  • On the mechanisms of transport and energy coupling in ABC exporters 

    Singh, Himansha (2018-07-21)
    The rapid emergence of multidrug resistant bacterial strains represents a major global healthcare issue. Amongst five known classes of membrane transporters, which play a huge role in multidrug efflux, primary-active ...

View more