Department of Clinical Neurosciences
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Clinical Applications of Neuromonitoring Following Acute Brain Injury
Various invasive and non-invasive cranial monitoring techniques can be applied clinically to describe the extent to which cerebral hemodynamics and subsequently, patient outcome, have been impacted following acute brain ... -
Positron emission tomography in vivo characterisation of the pathology of frontotemporal dementia
(2020-03-25)Frontotemporal dementia (FTD) is clinically and pathologically diverse, encompassing the behavioural variant FTD; non-fluent variant primary progressive aphasia; and semantic variant primary progressive aphasia. These are ... -
The brain microenvironment and its role in oligodendrocyte progenitor cell ageing
(2020-02-02)The overall aim of my thesis was to study age-related changes in molecular interplay between the brain extracellular matrix (ECM), oligodendrocyte progenitor cells (OPCs) and astrocytes. During ageing the resident brain ... -
Clinical aspects and in vitro modelling of GBA1 variant-associated Parkinson's disease
(2020-02-25)Parkinson’s disease (PD) is the second most common neurodegenerative disease, characterised by a typical movement disorder, accompanied by a number of non-motor manifestations including cognitive impairment, neuropsychiatric ...
