Department of Clinical Neurosciences
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Complex, yet Resolved: Time-, Frequency-, and Information-resolved Approaches to Brain Function and Human Consciousness
Different perturbations of the brain’s delicate functioning, ranging from transient pharmacological interventions to severe trauma, can result in altered states of consciousness. To illuminate how the neurobiology and ... -
Revealing Mechanisms of Sporadic Alzheimer’s Disease by Modelling in Organotypic Hippocampal Slice Cultures
Alzheimer’s disease (AD) is a devastating neurodegenerative condition which affects millions of people throughout the world. It is the most common form of dementia and manifests with progressive memory impairment and ... -
A sequencing-based analyisis of epigenetic modifications of the mitochondrial genome
Methylation on CpG residues is one of the most important epigenetic modifications of nuclear DNA, where it regulates gene expression. Methylation of mitochondrial DNA (mtDNA) has been studied using whole genome bisulfite ... -
The immunogenicity of embryonic stem cell-derived midbrain dopaminergic progenitors and its implications as a therapy to treat patients with Parkinson’s Disease
The progressive degeneration of the A9 dopaminergic (DA) neurons of the substantia nigra lies at the heart of the pathology of Parkinson’s disease (PD). Although current treatment options alleviate the symptoms, they do ...
