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  • Recent advances in epilepsy 

    Manford, M
    This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the ...
  • Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study 

    Kalincik, T; Brown, JWL; Robertson, N; Willis, M; Scolding, N; Rice, CM; Wilkins, A et al. (Elsevier, 2017-02-10)
    Background Alemtuzumab, an anti-CD52 antibody, is proven to be more efficacious than interferon beta-1a in the treatment of relapsing-remitting multiple sclerosis, but its efficacy relative to more potent immunotherapies ...
  • New insights into mechanisms of small vessel disease stroke from genetics 

    Tan, Y; Traylor, M; Rutten-Jacobs, L; Markus, H (Portland Press, 2017-04-01)
    Cerebral small vessel disease (SVD) is a common cause of lacunar strokes, vascular cognitive impairment (VCI) and vascular dementia. SVD is thought to result in reduced cerebral blood flow, impaired cerebral autoregulation ...
  • Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice 

    Kazanis, I; Evans, KA; Andreopoulou, E; Dimitriou, C; Koutsakis, C; Karadottir, RT; Franklin, RJM (Elsevier (Cell Press), 2017-03-14)
    wo populations of oligodendrogenic progenitors co-exist within the corpus callosum (CC) of the adult mouse. Local, parenchymal oligodendrocyte progenitor cells (pOPCs) and progenitors generated in the subependymal zone ...

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