Theses - Clinical Neurosciences
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Recent Submissions
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Using electrical stimulation responses to understand cochlear implant status
Cochlear implants (CIs) are neural prostheses that improve access to sounds for patients with severe to profound sensorineural hearing loss. CIs stimulate the auditory nerve with current pulses on a multi-electrode array ... -
The Mechanisms of Tau Entry to the Cytosol
The microtubule associated protein tau forms filamentous assemblies in the cytosol of neurons in several neurodegenerative diseases. In Alzheimer’s disease, tau pathology arises throughout the human brain in a spatio-temporal ... -
Rejuvenation of CNS Progenitors via Partial Reprogramming
Adult stem cells become less efficient at maintaining tissue integrity and repairing tissue damage with age. Oligodendrocyte progenitor cells (OPCs) are the largest population of stem cells in the adult CNS and give rise ... -
Progression and variation of Progressive Supranuclear Palsy
Progressive supranuclear palsy (PSP) is a devastating neurodegenerative disorder with poor prognosis. The development of novel therapeutics has been hindered by long delays from symptom onset to diagnosis, marked heterogeneity, ...
