Theses - Clinical Neurosciences
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Recent Submissions
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Tau pathology, microglia activation, and network dysfunction in Alzheimer’s disease
Tau pathology and neuroinflammation are key etio-pathogenetic mediators of Alzheimer’s disease (AD). Network dysfunction has also been reported in AD and linked to cognitive impairment. However, it is unclear how tau ... -
Dynamics of cerebral fluids in patients suffering from hydrocephalus and pseudotumour cerebri
This dissertation is devoted to dynamics of brain liquids in patients with altered CSF circulation and pressure-volume compensation. Since the introduction of intracranial pressure (ICP) monitoring, the studies of CSF ... -
Imaging and therapy in multiple sclerosis
(2020-05-20)Multiple sclerosis (MS) is a common, debilitating autoimmune disorder of the central nervous system (CNS). The most visible element of MS pathology is white matter (WM) lesions. However, extra-lesional abnormalities are ... -
The Effect of Manipulation of the Phosphoinositide 3-kinase Pathway on Axon Regeneration in vivo
(2020-10-01)Millions worldwide are visually impaired by optic nerve diseases, and glaucoma, the leading cause of irreversible blindness, is due to affect approximately 80 million people by 2020. The optic nerve is comprised of retinal ...
