Theses - Clinical Neurosciences
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Recent Submissions
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Characterising Peritumoural Progression of Glioblastoma using Multimodal MRI
(2017-10-03)Glioblastoma is a highly malignant tumor which mostly recurs locally around the resected contrast enhancement. However, it is difficult to identify tumor invasiveness pre-surgically, especially in non-enhancing areas. Thus, ... -
Effect of Parkinson’s disease-related alpha-synuclein abnormalities on the maturation of distinct iPSC-derived neuronal populations
(2017-10-03)Parkinson’s disease (PD) is the second most common age-related neurodegenerative condition. It is neuropathologically characterised by the presence of Lewy pathology and the degeneration of the midbrain dopaminergic neurons ... -
Optimization of the assessment of cerebral autoregulation in neurocritical care unit
(2017-06-01)Introduction Cerebral autoregulation (CA) refers to the physiological mechanisms in the brain to maintain constant blood flow despite changes in cerebral perfusion pressure (CPP). It plays an important protective role ... -
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and CNS remyelination
(2015-10-06)Remyelination is a regenerative process that occurs through the formation of myelin sheaths by oligodendrocytes, which are recruited as oligodendrocyte progenitor cells (OPCs) after demyelination in diseases such as Multiple ...
