Theses - Clinical Neurosciences
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Method Development of 13C, 1H and 31P Magnetic Resonance Spectroscopy for use in Traumatic Brain Injury
Traumatic brain injury (TBI) is a major health problem worldwide and is the leading cause of mortality and disability of young adults in the developed world. In vivo magnetic resonance spectroscopy (MRS) has proved to be ... -
Common Pathophysiological Features of Charcot-Marie-Tooth Disease
Hereditary peripheral neuropathy, also known as Charcot-Marie-Tooth disease (CMT) and related disorders, are a group of genetic disorders causing length-dependant neuropathy, resulting in motor and/or sensory loss progressing ... -
Immune responses to AAV gene therapy in the ocular compartment
Adeno-associated virus (AAV) is a viral vector that can be used to deliver therapeutic genes to diseased cells in the eye. Whilst some consider the eye to be an immuneprivileged organ, recent reports have begun to suggest ... -
Studying Myeloid Cell Heterogeneity After Spinal Cord Injury via Time-Resolved Single-Cell RNA Sequencing
Spinal cord injury (SCI) is a devastating pathology that affects thousands of individuals annually, resulting in the requirement for long-term physical and medical care and thus significant personal, societal, and economic ...
