Theses - Clinical Neurosciences
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Recent Submissions
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Modifications of perineuronal nets to regulate plasticity
(2019-07-01)Modifications of perineuronal nets to regulate plasticity Heleen Merel van ‘t Spijker Perineuronal nets (PNNs) are macromolecular structures formed by neurons after closure of critical periods of plasticity. During ... -
The role of GPR65 and GALC in Multiple Sclerosis
(2018-11-30)Genome-wide association studies have identified an extensive catalogue of unequivocally associated genetic variants, each of which provides a clue to the aetiology of multiple sclerosis (MS). Unfortunately, for the vast ... -
MODIFYING CHONDROITIN SULFATION ENHANCES RETINAL GANGLION CELL AXON REGENERATION
(2018-09-21)The failure of mammalian CNS neurons to regenerate their axons derives from a combination of intrinsic deficits and extrinsic obstacles. Following injury, chondroitin sulfate proteoglycans (CSPGs) accumulate within the ... -
Lewy Body Dementia and the Role of Inflammation
(2018-10-02)Background: Lewy body dementia (LBD), consisting of Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB), is known to make up more than 15% of dementia cases at autopsy, however the clinical prevalence ...
