Theses - Clinical Neurosciences
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Recent Submissions
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The role of the cold shock protein, RBM3, in cooling, synaptic structural plasticity and neuroprotection
(2019-11-30)Neurodegenerative diseases are characterised by the accumulation of misfolded proteins and the progressive loss of synapses, leading eventually to neuronal demise. Synapse loss occurs early in disease and is a reversible ... -
The pathophysiology of chronic subdural haematoma and the role of the dexamethasone
(2019-10-09)Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid overlying the surface of the brain, which is often treated with surgical drainage to prevent cerebral compression. Despite treatment it can ... -
The role of tau and neuroinflammation in Progressive Supranuclear Palsy and Alzheimer's Disease
(2020-05-16)The ability to assess the distribution and extent of tau pathology and neuroinflammation in Progressive Supranuclear Palsy (PSP) and Alzheimer’s disease (AD) ‘in vivo’ and to validate it using post mortem data is critical ... -
Multiple sclerosis associated SNPs influencing B cell expression of co-stimulatory receptors and T cell responses
(2020-01-27)Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) which has a complex aetiology that involves the interplay of both genetic and environmental factors. Although more ...
