Theses - Clinical Neurosciences
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(2018-10-20)Remyelination describes the regeneration of myelin sheaths, and is considered one of the most promising strategies for improving the prognosis of demyelinating diseases such as multiple sclerosis. Data from animal models ...
Neural stem cells respond to extracellular succinate via SUCNR1/GPR91 to ameliorate chronic neuroinflammation (2018-07-20)Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous system (CNS) diseases, in part by modulating adaptive and innate immune responses. Since metabolism governs the phenotype and ...
(2018-03-07)A carotid atherosclerotic plaque represents a nidus of inflammation mere centimetres below the blood-brain barrier. This inflammation, along with associated regions of microcalcification, are histopathological features of ...