Theses - Sanger Instititute
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Recent Submissions
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Understanding Inflammatory Bowel Disease using High-Throughput Sequencing
(2017-07-07)For over two decades, the study of genetics has been making significant progress towards understanding the causes of common disease. Across a wide range of complex disorders there have been hundreds of associated loci ... -
Regulation of gene expression in macrophage immune response
(2017-02-16)Gene expression quantitative trait loci (eQTL) mapping studies can provide mechanistic insights into the functions of disease-associated variants. However, many eQTLs are cell type and context specific. This is particularly ... -
Stage-specific profiling of the transcriptome during oogenesis and identification of a novel type of small RNA within the zebrafish ($\textit{Danio rerio}$)
(Wellcome Trust Sanger Institute, University of Cambridge, 2016-11-08)Developmental biology is an important field of study, as breakthroughs in this field can be used to understand aspects of evolution, more complex biological processes, and even diseases, such as cancer. Pathways and ... -
Identification and characterisation of host-pathogen protein-protein interactions in the blood stages of malaria
(2015-04-07)Malaria is a widespread and serious disease which affects billions of people. Protein-protein interactions occurring between host and Plasmodium parasites are critical to the pathogenesis of malaria and thus represent prime ...
