Department of Genetics
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Interplay of cis and trans mechanisms driving transcription factor binding and gene expression evolution (Springer Nature, 2017-10-23)Noncoding regulatory variants play a central role in the genetics of human diseases and in evolution. Here we measure allele-specific transcription factor binding occupancy of three liver-specific transcription factors ...
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements (Springer Nature, 2018-01-01)In animals, small RNA molecules termed PIWI-interacting RNAs (piRNAs) silence transposable elements (TEs), protecting the germline from genomic instability and mutation. piRNAs have been detected in the soma in a few ...