Department of Genetics
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Animal mitochondria produce cellular energy and rely on genes encoded within their own genome (mtDNA) in addition to those in the nucleus. mtDNA mutations are linked to mitochondrial and age-related diseases. Therefore, ...
The maternally inherited mitochondrial DNA (mtDNA) is a multi-copy genome that encodes several mitochondrial proteins essential for energy production. Heteroplasmy, the state of possessing multiple variants of mtDNA, is ...