Department of Genetics
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Analyses of RNA dynamics in Mus musculus
Ribonucleic acid (RNA) is a biological molecule that exists in the cell of virtually all kinds of known living organisms. Although its significance in fundamental cellular processes such as protein synthesis has been known ... -
Alternative splicing and single-cell RNA-sequencing: a feasibility assessment
We know little about how isoform choice is regulated in individual cells for most spliced genes. In theory, single-cell RNA-sequencing (scRNA-seq) could enable us to investigate isoform choice at cellular resolution. ... -
Variation-aware algorithms for cancer genome analysis
(2020-05-16)In this thesis, I explore variation-aware algorithms for analyzing cancer genomes. The scientific community has extensively catalogued millions of mutations present in cancer cells. This information is rarely used during ...
