Department of Genetics
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How to Mend a Broken Mitochondrial Genome: Mitochondrial Recombination And Its Applications
Animal mitochondria produce cellular energy and rely on genes encoded within their own genome (mtDNA) in addition to those in the nucleus. mtDNA mutations are linked to mitochondrial and age-related diseases. Therefore, ... -
Investigating the Regulation of Mitochondrial DNA Dynamics with a Drosophila Model
The maternally inherited mitochondrial DNA (mtDNA) is a multi-copy genome that encodes several mitochondrial proteins essential for energy production. Heteroplasmy, the state of possessing multiple variants of mtDNA, is ...
