Department of Genetics
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Investigating the genetic diversity, population structure and archaic admixture history in worldwide human populations using high-coverage genomes
(2019-10-26)I present the analysis on 929 high-coverage (>30x) genomes from the Human Genome Diversity Project (HGDP) panel, a collection of cell lines from 54 populations across the world. Some data processing steps were necessary ... -
Double-stranded RNA uptake in Caenorhabditis elegans
(2020-01-01)dsRNA uptake from the environment is a common phenomenon in many invertebrates and can be harnessed for acquiring pest control. In the nematode Caenorhabditis elegans, a transmembrane protein named systemic RNAi deficient-2 ... -
Inferring Determinants of Viral Transmission using Short-Read Sequence Data
(2019-11-30)In order to spread, pathogens must not only be able to grow within an infected host, but also transmit to found new infections. In this thesis, I present a new population genetic framework generating insights into viral ... -
Genetic requirements and molecular functions of 5-methylcytosine in Caenorhabditis elegans RNA
(2019-10-26)RNA molecules carry, in addition to their four canonical bases, a diverse range of chemically modified ribonucleosides. The methylation of carbon-5 of cytosines (m5C) in RNAs is a highly conserved and widely distributed ...
