Department of Genetics
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Novel roles of KAT2A chromatin complexes ATAC and SAGA in normal and malignant haematopoiesis
Haematopoiesis is a dynamic process by which the full array of blood cell types originates from multipotent haematopoietic stem cells (HSCs). The blood system has long been an attractive model to explore how cell fate ... -
Octopaminergic Regulation of Olfactory Discrimination in the Drosophila Larval Mushroom Body Calyx
(2021-09-17)The mushroom bodies of insect brains are essential for memory formation. The sensory input region of the mushroom bodies, the calyx, processes information received from stereotypic olfactory input channels, the Projection ... -
Efficient analysis and storage of large-scale genomic data
The impending advent of population-scaled sequencing cohorts involving tens of millions of individuals with matched phenotypic measurements will produce unprecedented volumes of genetic data. Storing and analysing such ... -
The role of non-genetic variability in Acute Myeloid Leukaemia
Acute myeloid leukaemia (AML) is a heterogeneous clonal disorder of haematopoietic progenitor cells with a dismal survival. It has a strong reliance on epigenetic and transcriptional factors for disease progression. ...
