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  • Extent, causes, and consequences of small RNA expression variation in human adipose tissue. 

    Parts, Leopold; Hedman, Åsa K; Keildson, Sarah; Knights, Andrew J; Abreu-Goodger, Cei; van de Bunt, Martijn; Guerra-Assunção, José Afonso et al. (2012-01)
  • Interplay of cis and trans mechanisms driving transcription factor binding and gene expression evolution 

    Wong, Emily S; Schmitt, Bianca M; Kazachenka, Anastasiya; Thybert, David; Redmond, Aisling; Connor, Frances; Rayner, Tim F et al. (Springer Nature, 2017-10-23)
    Noncoding regulatory variants play a central role in the genetics of human diseases and in evolution. Here we measure allele-specific transcription factor binding occupancy of three liver-specific transcription factors ...
  • siRNA screen identifies QPCT as a druggable target for Huntington's disease. 

    Jimenez-Sanchez, Maria; Lam, Wun; Hannus, Michael; Sönnichsen, Birte; Imarisio, Sara; Fleming, Angeleen Louise; Tarditi, Alessia et al. (2015-05)
  • Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements 

    Lewis, Samuel Howard; Quarles, KA; Yang, Y; Tanguy, M; Frezal, L; Smith, SA; Sharma, PP et al. (Springer Nature, 2018-01-01)
    In animals, small RNA molecules termed PIWI-interacting RNAs (piRNAs) silence transposable elements (TEs), protecting the germline from genomic instability and mutation. piRNAs have been detected in the soma in a few ...

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