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  • Patterns of atrophy in pathologically confirmed dementias: a voxelwise analysis 

    Harper, L; Bouwman, F; Burton, EJ; Barkhof, F; Scheltens, P; O'Brien, JT; Fox, NC et al.
    $\textbf{OBJECTIVE}$: Imaging is recommended to support the clinical diagnoses of dementias, yet imaging research studies rarely have pathological confirmation of disease. This study aims to characterise patterns of brain ...
  • Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease 

    Mak, E; Su, L; Williams, GB; Firbank, MJ; Lawson, RA; Yarnall, AJ; Duncan, GW et al. (Elsevier BV, 2017-07-01)
    We investigated whole-brain atrophy and ventricular enlargement over 18 months in nondemented Parkinson's disease (PD) and examined their associations with clinical measures and baseline CSF markers. PD subjects (n = 100) ...
  • In vivo tau PET imaging in dementia: Pathophysiology, radiotracer quantification, and a systematic review of clinical findings. 

    Hall, B; Mak, E; Cervenka, S; Aigbirhio, FI; Rowe, JB; O'Brien, JT (Elsevier BV, 2017-07-01)
    In addition to the deposition of β-amyloid plaques, neurofibrillary tangles composed of aggregated hyperphosphorylated tau are one of the pathological hallmarks of Alzheimer's disease and other neurodegenerative disorders. ...
  • Immunopsychiatry: important facts 

    Khandaker, GM; Dantzer, R; Jones, PB (Cambridge University Press, 2017-04-18)
    Accumulating evidence indicate a role for the immune system particularly inflammation and autoimmunity in the aetiology of major psychiatric disorders such as depression and schizophrenia. In this paper, we discuss some ...

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