Cambridge Centre for Brain Repair
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Differential regenerative ability of sensory and motor neurons.
(Elsevier BV, 2017-06-23)After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve ... -
The Genetic Basis of Cognitive Impairment and Dementia in Parkinson's Disease.
(Frontiers Media SA, 2016)Cognitive dysfunction is a common feature of Parkinson's disease (PD) with mild cognitive impairment affecting around a quarter of patients in the early stages of their disease, and approximately half developing dementia ... -
Intratumor heterogeneity and transcriptional profiling in glioblastoma: Translational opportunities
(Future Medicine Ltd, 2015-08)<jats:p> The study of phenotypic and genetic intratumor heterogeneity in glioblastoma is attracting a lot of attention. Recent studies have demonstrated that transcriptional profiling analysis can help interpret the ... -
Retinal ganglion cell survival and axon regeneration in WldS transgenic rats after optic nerve crush and lens injury.
(Springer Science and Business Media LLC, 2012-06-06)BACKGROUND: We have previously shown that the slow Wallerian degeneration mutation, whilst delaying axonal degeneration after optic nerve crush, does not protect retinal ganglion cell (RGC) bodies in adult rats. To test ...
