Cambridge Centre for Brain Repair
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(Elsevier, 2017-06)After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve ...
(Frontiers, 2016-05-20)Cognitive dysfunction is a common feature of Parkinson’s disease (PD) with mild cognitive impairment affecting around a quarter of patients in the early stages of their disease, and approximately half developing dementia ...
Retinal ganglion cell survival and axon regeneration in WldS transgenic rats after optic nerve crush and lens injury (2012-06-06)Abstract Background We have previously shown that the slow Wallerian degeneration mutation, whilst delaying axonal degeneration after optic nerve crush, does not protect retinal ganglion cell (RGC) bodies in adult rats. ...