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Recent Submissions

  • New PomBase Website 2017, Group Leader Survey Summary 

    Wood, Valerie; Harris, Midori; Lock, Antonia; Rutherford, Kim (2017-12-01)
    PomBase launched a new version of its website on 25th October 2017. Shortly thereafter, 100 fission yeast research group leaders were surveyed to gauge the impact of the site redesign.
  • Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. 

    Luis, Ana S; Briggs, Jonathon; Zhang, Xiaoyang; Farnell, Benjamin; Ndeh, Didier; Labourel, Aurore; Baslé, Arnaud et al. (Nature, 2018-02)
    The major nutrients available to human colonic Bacteroides species are glycans, exemplified by pectins, a network of covalently linked plant cell wall polysaccharides containing galacturonic acid (GalA). Metabolism of ...
  • SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements 

    Dang Do, Vinh; Strauss, Bernhard; Cukuroglu, Engin; Macaulay, Iain; Boon Wee, Keng; Xiamoming, Tim; Ruiz De Los Mozos, Igor et al. (Springer Nature, 2018)
    The RNA-binding protein SRSF3 (also known as SRp20) has critical roles in the regulation of pre-mRNA splicing. Zygotic knockout of Srsf3 results in embryo arrest at the blastocyst stage. However, SRSF3 is also present in ...
  • Sub-minute kinetics of human red cell fumarase: 1 H spin-echo NMR spectroscopy and 13 C rapid-dissolution dynamic nuclear polarization. 

    Shishmarev, Dmitry; Wright, Alan J; Rodrigues, Tiago B; Pileio, Giuseppe; Stevanato, Gabriele; Brindle, Kevin M; Kuchel, Philip W (Wiley-Blackwell, 2018-03)
    Fumarate is an important probe of metabolism in hyperpolarized magnetic resonance imaging and spectroscopy. It is used to detect the release of fumarase in cancer tissues, which is associated with necrosis and drug treatment. ...

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