Scholarly Works - Clinical Biochemistry
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Recent Submissions
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The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.
(Wiley-Blackwell, 2018-02-21)The intracellular function of myosin motors requires a number of adaptor molecules, which control cargo attachment, but also fine-tune motor activity in time and space. These motor-adaptor-cargo interactions are often weak, ... -
Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights.
(Elsevier, 2018-02-07)Objective: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain and adiposity. However, little is known about the mechanisms by ... -
GDF15 and metabolism: homing in on a new therapy
Three recent studies in mice have identified a specific receptor, GFRAL, for the known anorectic peptide GDF15, increasing the mechanistic understanding of its effect and paving the way for the development of novel ...
