Scholarly Works - Clinical Biochemistry
About this collection
The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics. (Wiley-Blackwell, 2018-02-21)The intracellular function of myosin motors requires a number of adaptor molecules, which control cargo attachment, but also fine-tune motor activity in time and space. These motor-adaptor-cargo interactions are often weak, ...
Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights. (Elsevier, 2018-02-07)Objective: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain and adiposity. However, little is known about the mechanisms by ...
Three recent studies in mice have identified a specific receptor, GFRAL, for the known anorectic peptide GDF15, increasing the mechanistic understanding of its effect and paving the way for the development of novel ...