Scholarly Works - Obstetrics and Gynaecology
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ELABELA/APELA Levels Are Not Decreased in the Maternal Circulation or Placenta among Women with Preeclampsia.
(Elsevier BV, 2018-08)The genetic deletion of apelin receptor early endogenous ligand (Elabela; official name APELA) produces a preeclampsia-like phenotype in mice. However, evidence linking ELABELA with human disease is lacking. Therefore, we ... -
Screening for fetal growth restriction using ultrasound and the sFLT1/PlGF ratio in nulliparous women: a prospective cohort study
(Elsevier, 2018-08)ABSTRACT Background Fetal growth restriction is a major determinant of perinatal morbidity and mortality. The condition has no gold standard definition but a widely used proxy is delivery of a small for gestational age ... -
Correcting for optimistic prediction in small data sets.
(Oxford University Press (OUP), 2014-08-01)The C statistic is a commonly reported measure of screening test performance. Optimistic estimation of the C statistic is a frequent problem because of overfitting of statistical models in small data sets, and methods exist ... -
Universal screening for foetal growth restriction.
(Elsevier BV, 2018-05)Foetal growth restriction (FGR) is a major cause of morbidity and mortality. Clinical methods for identifying women whose pregnancies are affected by FGR do not perform well. Despite this, the current approach to screening ...