Scholarly Works - Physiology, Development and Neuroscience
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Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease. (University of Chicago Press, 2018-03)Genetic variation modulating risk of sporadic Parkinson's disease (PD) has been primarily explored through genome wide association studies (GWAS). However, like many other common genetic diseases, the impacted genes remain ...
(Wiley-Blackwell, 2018-02)Increasing evidence implicates chronic energetic dysfunction in human cardiac arrhythmias. Mitochondrial impairment through Pgc-1β knockout is known to produce a murine arrhythmic phenotype. However, the cumulative effect ...
Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation. (Elsevier, 2017-11)Introduction: Throughout pregnancy, the placenta dynamically changes as trophoblast progenitors differentiate into mature trophoblast cell subtypes. This process is in part controlled by epigenetic regulation of DNA ...