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Recent Submissions

  • A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells. 

    Fang, Fang; Angulo, Benjamin; Xia, Ninuo; Sukhwani, Meena; Wang, Zhengyuan; Carey, Charles C; Mazurie, Aurélien et al. (Springer Nature, 2018-06)
    Dysregulation of genetic pathways during human germ cell development leads to infertility. Here, we analysed bona fide human primordial germ cells (hPGCs) to probe the developmental genetics of human germ cell specification ...
  • In vitro generation of mouse polarized embryo-like structures from embryonic and trophoblast stem cells 

    Harrison, sarah ellys; Sozen, berna; Zernicka-Goetz, magdalena (Springer Nature, 2018-07)
    Mammalian embryogenesis requires the coordination of embryonic and extra-embryonic tissues to enable implantation into the uterus and post-implantation development to establish the body plan. Mouse embryonic stem cells ...
  • IFPA meeting 2017 workshop report: Clinical placentology, 3D structure-based modeling of placental function, placental bed, and treating placental dysfunction. 

    Acharya, Ganesh; Aplin, John; Brownbill, Paul; Bulmer, Judith; Burton, Graham; Chamley, Larry; Chernyavsky, Igor et al. (Elsevier, 2018-04)
    Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2017 there were four themed workshops, all of which are summarized in this report. These workshops ...
  • Tracing cellular dynamics in tissue development, maintenance and disease. 

    Rulands, Steffen; Simons, Benjamin D (Elsevier BV, 2016-12)
    The coordination of cell proliferation and differentiation is central to the development and maintenance of tissues, while its dysregulation underlies the transition to diseased states. By combining lineage tracing with ...

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