Scholarly Works - Physiology, Development and Neuroscience
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Recent Submissions
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Arrhythmic effects of Epac-mediated ryanodine receptor activation in Langendorff-perfused murine hearts are associated with reduced conduction velocity
(Wiley, 2017-03)Recent papers have attributed arrhythmic substrate in murine RyR2-P2328S hearts to reduced action potential (AP) conduction velocities (CV), reflecting acute functional inhibition and/or reduced expression of sodium channels. ... -
The anatomy of phenotype ontologies: principles, properties and applications
(Oxford University Press, 2017-04-06)The past decade has seen an explosion in the collection of genotype data in domains as diverse as medicine, ecology, livestock and plant breeding. Along with this comes the challenge of dealing with the related phenotype ... -
Geometry can provide long-range mechanical guidance for embryogenesis
(PLoS, 2017-03-27)Downstream of gene expression, effectors such as the actomyosin contractile machinery drive embryo morphogenesis. During $\textit{Drosophila}$ embryonic axis extension, actomyosin has a specific planar-polarised organisation, ... -
The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo
(The Company of Biologists, 2017-04-15)The separation of embryonic from extra-embryonic tissues within the inner cell mass to generate the epiblast (EPI), which will form the new organism, from the primitive endoderm (PE), which will form the yolk sac, is a ...
