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Recent Submissions

  • Participants’ perspectives and preferences on clinical trial result dissemination: The TRUST Thyroid Trial experience 

    Sinnott, Carol; Racine, Emmy; Hurley, Caroline; Cheung, Aoife; Kearney, Patricia; Smithson, Henry (F1000 Research, 2018-04-12)
    Background: While there is an increasing consensus that clinical trial results should be shared with trial participants, there is a lack of evidence on the most appropriate methods. The aim of this study is to use a patient ...
  • Community-based pre-pregnancy care programme improves pregnancy preparation in women with pregestational diabetes. 

    Yamamoto, Jennifer M; Hughes, Deborah JF; Evans, Mark; Karunakaran, Vithian; Clark, John DA; Morrish, Nicholas J; Rayman, Gerry A et al. (Springer, 2018-05-09)
    AIMS/HYPOTHESIS: Women with diabetes remain at increased risk of adverse pregnancy outcomes associated with poor pregnancy preparation. However, women with type 2 diabetes are less aware of and less likely to access ...
  • The MR-Base platform supports systematic causal inference across the human phenome. 

    Hemani, Gibran; Zheng, Jie; Elsworth, Benjamin; Wade, Kaitlin H; Haberland, Valeriia; Baird, Denis; Laurin, Charles et al. (eLife Sciences Publications, 2018-05-30)
    Results from genome-wide association studies (GWAS) can be used to infer causal relationships between phenotypes, using a strategy known as 2-sample Mendelian randomization (2SMR) and bypassing the need for individual-level ...
  • Inferring Causal Relationships Between Risk Factors and Outcomes from Genome-Wide Association Study Data. 

    Burgess, Stephen; Foley, Christopher; Zuber, Verena (Annual Reviews, Inc., 2018-08)
    An observational correlation between a suspected risk factor and an outcome does not necessarily imply that interventions on levels of the risk factor will have a causal impact on the outcome (correlation is not causation). ...

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