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  • Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. 

    Seibert, Tyler M; Fan, Chun Chieh; Wang, Yunpeng; Zuber, Verena; Karunamuni, Roshan; Parsons, J Kellogg; Eeles, Rosalind A et al.
    Objectives: Prostate-specific-antigen (PSA) screening resulted in reduced prostate cancer (PCa) mortality in a large clinical trial, but due to many false positives and overdiagnosis of indolent disease, many guidelines ...
  • Weight change and 15 year mortality: results from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study. 

    Mulligan, Angela Assumpta; Lentjes, Maria Antonetta; Luben, Robert; Wareham, Nicholas John; Khaw, Kay-Tee (Springer Nature, 2017-12-20)
    Studies have reported a higher mortality risk associated with weight loss, particularly in middle-aged and older adults, although some of these studies did find that gaining weight was also associated with an increased ...
  • Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer 

    Loveday, Chey; Easton, Douglas Frederick
    Testicular germ cell tumor (TGCT), the most common cancer in men aged 18 to 45 years, has a strong heritable basis. Genome-wide association studies (GWAS) have proposed single nucleotide polymorphisms (SNPs) at a number ...
  • Effect of glass markings on drinking rate in social alcohol drinkers. 

    Troy, David M; Attwood, Angela S; Maynard, Olivia M; Scott-Samuel, Nicholas E; Hickman, Matthew; Marteau, Theresa; Munafò, Marcus R (OUP, 2017-04)
    Background: The main aim of these studies was to explore the influence of volume information on glassware on the time taken to consume an alcoholic beverage. Methods: In Study 1, male and female social alcohol consumers ( ...

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