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dc.contributor.authorIshihara, Lianna Sen
dc.contributor.authorKhaw, Kay-Teeen
dc.contributor.authorLuben, Roberten
dc.contributor.authorBingham, Sheilaen
dc.contributor.authorWelch, Ailsaen
dc.contributor.authorDay, Nicholas Een
dc.contributor.authorBrayne, Carolen
dc.date.accessioned2011-06-16T16:51:13Z
dc.date.available2011-06-16T16:51:13Z
dc.date.issued2005-08-24en
dc.identifier.citationBMC Neurology 2005, 5:15
dc.identifier.issn1471-2377
dc.identifier.urihttp://www.dspace.cam.ac.uk/handle/1810/238095
dc.description.abstractAbstract Background Parkinsonian symptoms have been associated with increased morbidity and mortality. Several studies have reported on the prevalence of signs and symptoms. Symptoms questionnaires can identify potential PD cases for further neurological examination to save resources. They can also provide information about how much of the population reports specific signs and symptoms. The objective of the study was to determine the self-reported prevalence of parkinsonian symptoms from a questionnaire, and to examine their association with age and self-reported Parkinson's disease in a large cohort. Methods A cross-sectional study was conducted within a sub-cohort of the EPIC-Norfolk (European Prospective Investigation of Cancer) cohort study. Results The prevalence of six self-reported parkinsonian symptoms are reported for 11539 individuals who answered all symptoms questions (62% of sub-cohort): rest tremor (4%), difficulty starting to walk (4%), difficulty getting out of a chair (6%), slower walking (34%), smaller handwriting (micrographia- 9%), and less acute sense of smell (olfactory dysfunction- 9%). The presence of individual symptoms increased with age except for difficulty getting out of a chair. Conclusion The results support previous findings that the presence of self-reported parkinsonian symptoms is strongly associated with age and self-reported PD diagnosis. The data also provide information regarding the prevalence of symptoms in a large, younger population of adults than previously reported in the literature.
dc.languageEnglishen
dc.language.isoen
dc.titleSelf-reported parkinsonian symptoms in the EPIC-Norfolk cohorten
dc.typeArticle
dc.date.updated2011-06-16T16:51:13Z
dc.description.versionRIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.en
dc.rights.holderIshihara et al.; licensee BioMed Central Ltd.
prism.publicationDate2005en
rioxxterms.versionofrecord10.1186/1471-2377-5-15en
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2005-08-24en
dc.contributor.orcidKhaw, Kay-Tee [0000-0002-8802-2903]
dc.contributor.orcidLuben, Robert [0000-0002-5088-6343]
dc.contributor.orcidBrayne, Carol [0000-0001-5307-663X]
dc.identifier.eissn1471-2377
rioxxterms.typeJournal Article/Reviewen


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