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Recent Submissions

  • Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types 

    Ecker, S; Chen, L; Pancaldi, V; Bagger, FO; Fernández, JM; Carrillo de Santa Pau, E; Juan, D et al. (BioMed Central, 2017-01-26)
    Background A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. Results We apply a novel ...
  • Life, health, and safety of industrial workers in bangladesh: should they be driven by economic rationale or moral imperative? 

    Chowdhury, R; Harshfield, E; Roy, S; Flora, MS; Akram, KAHM; Bhuiya, A; Ahsan, H (Lippincott Williams & Wilkins Ltd., 2014-04)
    Recent disasters caused by human negligence have gained widespread global attention. The devastating Savar building collapse in Bangladesh in April 2013 has been described as the deadliest industrial accident and worst ...
  • Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer 

    Dite, GS; MacInnis, RJ; Bickerstaffe, A; Dowty, JG; Milne, RL; Antoniou, AC; Weideman, P et al. (Oxford University Press, 2017-03-15)
    The ability to classify people according to their underlying genetic susceptibility to a disease is increasing with new knowledge, better family data, and more sophisticated risk prediction models, allowing for more effective ...
  • Genetic invalidation of Lp-PLA$_{2}$ as a therapeutic target: Large-scale study of five functional Lp-PLA$_{2}$-lowering alleles 

    Gregson, JM; Freitag, DF; Surendran, P; Stitziel, NO; Chowdhury, R; Burgess, S; Kaptoge, S et al. (SAGE Publications Ltd, 2017-03-01)
    $\textbf{Aims}$ Darapladib, a potent inhibitor of lipoprotein-associated phospholipase A$_{2}$ (Lp-PLA$_{2}$), has not reduced risk of cardiovascular disease outcomes in recent randomized trials. We aimed to test whether ...

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