Cancer Research UK Cambridge Institute
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Type 2 Innate Lymphoid Cells (ILC2s) are recently discovered tissue resident immune cells, studied more commonly in barrier tissues like the lung and intestine. ILC2s are critical mediators of early type-2 immune responses ...
High grade serous ovarian carcinoma (HGSOC) is the most common subtype of ovarian cancer and the major cause of gynaecological cancer-related deaths in the Western world. Overall survival for HGSOC patients has not improved ...
Blood vessel networks in tumours are often chaotic, dense and immature resulting in reduced blood perfusion and oxygen delivery, leading to hypoxia (low oxygen levels). Hypoxic tumours are more aggressive, therapy resistant ...