Cancer Research UK Cambridge Institute
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Analysing the relationship between immune infiltration and tissue architecture in high grade serous ovarian cancer (2021-01-10)The aim of this project was to understand the distribution and compartmental effects of immune populations and the tissue architecture that underlies them in high grade serous ovarian cancer (HGSOC). The quantitative ...
Oncogene-induced senescence (OIS) is a well-described autonomous tumour suppressor mechanism which removes cells harbouring oncogenic mutations from the proliferation pool. However, senescent cells remain metabolically ...
An appreciation of the complexity of the mammalian transcriptome has expanded our understanding of eukaryotic genome regulation with the discoveries of functional non-coding ribonucleic acids (RNAs). In recent years, the ...