Cancer Research UK Cambridge Institute
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(eLife Sciences Publications Ltd, 2016-11-01)Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.
Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours (Springer Nature, 2017-06-27)Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, ...
(American Society of Clinical Oncology, 2017-07-20)Modern imaging techniques, particularly functional imaging techniques that interrogate some specific aspect of underlying tumor biology, have enormous potential in neuro-oncology for disease detection, grading, and tumor ...
(Public Library of Science (PLoS), 2017-04-03)Maps of genetic interactions can dissect functional redundancies in cellular networks. Gene expression profiles as high-dimensional molecular readouts of combinatorial perturbations provide a detailed view of genetic ...