Cancer Research UK Cambridge Institute
About this community
Sub-communities within this community
Collections in this community
Recent Submissions
-
A CRISPR resource for individual, combinatorial, or multiplexed gene knockout
(Cell Press, 2017-07-04)We have combined a machine-learning approach with other strategies to optimize knockout-efficiency with the CRISPR/Cas9 system. In addition, we have developed a multiplexed sgRNA expression strategy that promotes the ... -
Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition
(Cell Press, 2017-07)The early cell divisions of many metazoan embryos are rapid and occur in the near absence of transcription. At the mid-blastula transition (MBT) the cell cycle elongates and several processes become established including ...
