Theses - Cancer Research UK Cambridge Institute
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Recent Submissions
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Detecting tumour responses to treatment using metabolic imaging with hyperpolarised [1-13C]pyruvate and 2-([18F]fluoro)-2-deoxy-D-glucose
(2019-08-01)Earlier detection of tumour responses to treatment would facilitate modification of treatment regimens and reduce unnecessary side effects and the costs of ineffective therapy. Anatomical changes following treatment are ... -
Studying early development using droplet single-cell RNA sequencing
In complex organisms, each individual derives from a single fertilised ovum. This process of development is characterised by an increase in cell number and a diversification of the various cell types that are present. ... -
Autophagy maintains the homeostatic environment in the male reproductive organs playing a key role in fertility
(2019-10-16)Autophagy is an evolutionarily conserved recycling process that plays a crucial role in maintaining cellular homeostasis. It has been reported that autophagy is closely involved in the physiological process of spermatogenesis ... -
Development of Magnetic Resonance Spectroscopic Imaging Methods to Assess Tumour Metabolism
(2019-10-26)Proton detection of hyperpolarized low gamma nuclei. Hyperpolarized molecules labelled with low gamma nuclei such as 15N and 13C have been proposed as magnetic resonance spectroscopic imaging (MRSI) agents for investigating ...
