Theses - Cancer Research UK Cambridge Institute
About this collection
Recent Submissions
-
Studying the Clonal Origins of Drug Resistance in Human Breast Cancers
(2019-05-18)Despite remarkable advances in our understanding of the drivers of human malignancies, new targeted therapies often fail to show sufficient efficacy in clinical trials. Indeed, the cost of bringing a new agent to market ... -
The clonal architecture and tumour microenvironment of breast cancers are shaped by neoadjuvant chemotherapy
(2019-04-27)Neoadjuvant chemotherapy has become standard practice in patients with high-risk early breast cancer as it improves rates of breast conservation surgery and enables prediction of recurrence and survival by using response ... -
Characterisation of the Tumour Microenvironment in Ovarian Cancer
(2019-03-18)The tumour microenvironment comprises the non-cancerous cells present in the tumour mass (fibroblasts, endothelial, and immune cells), as well as signalling molecules and extracellular matrix. Tumour growth, invasion, ...
