About this collection

Recent Submissions

  • Latent feature models and non-invasive clonal reconstruction 

    Marass, Francesco (2017-07-22)
    Intratumoural heterogeneity complicates the molecular interpretation of biopsies, as multiple distinct tumour genomes are sampled and analysed at once. Ignoring the presence of these populations can lead to erroneous ...
  • Estrogen receptor beta modulates prostate carcinogenesis 

    Nelson, Adam William (2017-10-01)
    Prostate cancer (PC) is characterised by dependence upon androgen receptor (AR) as its driving oncogene. When organ-confined, radical treatment can be curative, however there is no cure for advanced, castration-resistant ...
  • Functional characterisation of driver events in ovarian clear cell carcinoma 

    Gounaris, Ioannis (2014-11-11)
    Ovarian clear cell carcinoma (OCCC) is a distinct subtype of epithelial ovarian cancer (EOC) characterised by glycogen accumulation. Frequently arising within endometriotic cysts, it can be conceived as an ectopic ...