Theses - Cancer Research UK Cambridge Institute
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Therapeutic targeting of the DNA damage response (DDR), coupled with the implementation of personalised treatment strategies, has the potential to improve the poor survival outcomes of pancreatic ductal adenocarcinoma ...
(2020-11-30)Highly recurrent chromosome translocations that produce oncogenic fusions are a prime example of practical therapeutic targets translating into clinical successes. We have previously described the genetic driver of ...
When cells divide, mistakes happen. However, an intricate surveillance system has evolved to detect and eliminate anomalous cells before they become detrimental to the host organism. In cancer, abnormal cells manage to ...