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  • Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury. 

    Hong, Young Tea; Veenith, Tonny; Dewar, Deborah; Outtrim, Joanne Gaye; Mani, Vaithianadan; Williams, Claire; Pimlott, Sally et al. (2014-01)
    OBJECTIVES: To image amyloid deposition in patients with traumatic brain injury (TBI) using carbon 11-labeled Pittsburgh Compound B ([11C]PiB) positron emission tomography (PET) and to validate these findings using ...
  • Validation of reference tissue modelling for [11C]flumazenil positron emission tomography following head injury. 

    Geeraerts, Thomas; Coles, Jonathan Peter; Aigbirhio, Franklin Imo; Pickard, John Douglas; Menon, David Krishna; Fryer, Timothy David; Hong, Young Tea (2011-07)
    OBJECTIVE: [(11)C]Flumazenil ([(11)C]FMZ) positron emission tomography (PET) can be used as a measure of neuronal loss. The purpose of this study was to validate reference tissue kinetic modelling of [(11)C]FMZ PET within ...
  • Use of diffusion tensor imaging to assess the impact of normobaric hyperoxia within at-risk pericontusional tissue after traumatic brain injury 

    Veenith, TV; Carter, EL; Grossac, J; Newcombe, Virginia; Outtrim, Joanne Gaye; Nallapareddy, S; Lupson, V et al. (2014-10-01)
    Ischemia and metabolic dysfunction remain important causes of neuronal loss after head injury, and we have shown that normobaric hyperoxia may rescue such metabolic compromise. This study examines the impact of hyperoxia ...
  • Elevated blood GFAP and UCH-L1 levels in acute orthopaedic injuries without CNS involvement 

    Posti, Jussi; Hossain, Iftakher; Takala, Riikka; Liedes, Hilkka; Newcombe, Virginia; Outtrim, Joanne; Katila, Ari et al. (2016)
    Objectives: Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) are considered to be both sensitive and specific for TBI in acute injury diagnostics. The objective of this study is to ...

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