MRC Epidemiology Unit
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Using human genomics to decipher biological mechanisms underlying reproductive ageing and fertility in women
Women are born with a non-renewable ovarian reserve, which is depleted throughout reproductive life. When this reserve is exhausted, they experience menopause and cease ovulating. Importantly, menopause timing is highly ... -
Detection, causes and consequences of sex chromosome mosaicism
Sex chromosome mosaicism, including male mosaic loss of chromosome Y (LOY) and female mosaic loss of chromosome X (LOX), is the most common form of clonal haematopoiesis (CH) that can be defined as the age-related clonal ... -
What influences government policymaking? The case of childhood obesity in England
Abstract What influences government policymaking? The case of childhood obesity in England | Dolly Rose Zarina Theis In England today, four out of the top five risk factors of healthy life years lost to death, disability ... -
The role of mental health in adult behavioural weight management interventions
Established evidence reports that there is a bidirectional relationship between obesity and mental health, with obesity as both a cause and consequence of poor mental health. Treatments for obesity and poor mental health ...
