MRC Epidemiology Unit
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Investigating the Role of Inflammatory Biomarkers and Incretins in the Aetiology of Type 2 Diabetes and Coronary Heart Disease using Human Genetics
Background: The relevance of inflammatory and incretin-related signalling pathways in the aetiology of cardiometabolic diseases is of considerable pharmacological interest but remains uncertain. Evidence from animal models ... -
Digital phenotyping through multimodal, unobtrusive sensing
(2021-02-23)The growing adoption of multimodal wearable and mobile devices, such as smartphones and wrist-worn watches has generated an increase in the collection of physiological and behavioural data at scale. This digital phenotyping ... -
Common 'Inborn Errors' of Metabolism in the General Population
(2021-03-23)Inborn errors of metabolism (IEMs) are a group of disorders characterised by the toxic accumulation or deficiency of circulating molecules (‘metabolites’) caused by rare genetic mutations. Previous studies have identified ... -
A mixed methods investigation of factors influencing decision-making for new active living infrastructure in different contexts
Physical inactivity increases the risk of many non-communicable diseases. The built environment is an important determinant of physical activity and the ways in which places are designed and built may lock in, or out, ...
