MRC Epidemiology Unit
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Aetiological role of early lifestyle exposures in puberty timing
Amidst the global secular trends towards earlier timing of pubertal development, there are abundant evidence from various populations that early puberty timing is associated with higher risks for a wide range of subsequent ... -
Investigation of Genetic and Behavioural Determinants of Type 2 diabetes and Glycaemic Traits
Type 2 diabetes (T2D) is a complex chronic disease which is associated with micro- and macro-vascular complications and premature mortality. This multifactorial disease originates from a complex interplay between genetic, ... -
Changes to marketing in response to sugary beverage taxation: the Soft Drinks Industry Levy in the United Kingdom
Background: Overall sugar intake in the United Kingdom (UK) continues to exceed recommended levels. As high sugar consumption contributes to multiple non-communicable diseases, the World Health Organization recommends the ... -
Investigating the Role of Inflammatory Biomarkers and Incretins in the Aetiology of Type 2 Diabetes and Coronary Heart Disease using Human Genetics
Background: The relevance of inflammatory and incretin-related signalling pathways in the aetiology of cardiometabolic diseases is of considerable pharmacological interest but remains uncertain. Evidence from animal models ...
