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Recent Submissions

  • Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study 

    Perrot, N; Verbeek, R; Sandhu, M; Boekholdt, SM; Hovingh, GK; Wareham, NJ; Khaw, K-T et al. (Elsevier, 2017-01)
    BACKGROUND AND AIMS: Lipoprotein(a) (Lp[a]) is a strong genetic risk factor for cardiovascular disease (CVD). The American Heart Association has prioritised seven cardiovascular health metrics to reduce the burden of CVD: ...
  • PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study 

    Schmidt, AF; Swerdlow, DI; Holmes, MV; Patel, RS; Fairhurst-Hunter, Z; Lyall, DM; Hartwig, FP et al. (Elsevier BV, 2017-02)
    BACKGROUND: Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but also with modest ...
  • Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition 

    Perez-Cornago, A; Appleby, PN; Tipper, S; Key, TJ; Allen, NE; Nieters, A; Vermeulen, R et al. (John Wiley & Sons Inc., 2017-01-18)
    Insulin-like growth factor (IGF)-I has cancer promoting activities. However, the hypothesis that circulating IGF-I concentration is related to risk of lymphoma overall or its subtypes has not been examined prospectively. ...
  • Obesity-induced hypoadiponectinemia: the opposite influences of central and peripheral fat compartments 

    Borges, MC; Oliveira, IO; Freitas, DF; Ong, K; Gigante, DP; Barros, AJD

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