Tandem isomerization/telomerization of long chain dienes.
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Authors
Torrente-Murciano, Laura
Nielsen, David J
Cavell, Kingsley J
Lapkin, Alexei A
Abstract
The first example of a tandem reaction involving double-bond migration in combination with telomerization is reported. Homogeneous and heterogeneous Ru catalysts were employed as isomerization catalysts, and telomerization was realized using a homogeneous Pd(0) precursor complex with a N-heterocyclic carbene (IMes) ligand. Overall conversions approaching 60% were achieved with the best selectivity to telomerization products of 91% attained at 11% conversion. Conversion was markedly higher in the presence of longer-chain alcohol (1-butanol) as the nucleophile (telogen).
Description
Keywords
C-C coupling reactions, carbenes, isomerization, tandem reaction, telomerization, transition metals
Journal Title
Front Chem
Conference Name
Journal ISSN
2296-2646
2296-2646
2296-2646
Volume Title
2
Publisher
Frontiers Media SA
Publisher DOI
Sponsorship
Financial support from Engineering and Physical Sciences Research Council (EPSRC, UK) via grant GR/S86112/01 is gratefully acknowledged.