Scholarly Works - Institute of Metabolic Science
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A Protocol for Producing the Maternal Low-Protein Rat Model: A Tool for Preclinical Proteomic Studies (Springer, 2017-03-29)Epidemiological studies have shown that periods of poor nutrition during pregnancy can lead to an increased risk of metabolic and psychiatric disorders in the offspring. In addition, some individuals with disorders such ...
Unconventional Transport Routes of Soluble and Membrane Proteins and Their Role in Developmental Biology (MDPI AG, 2017-03-25)Many proteins and cargoes in eukaryotic cells are secreted through the conventional secretory pathway that brings proteins and membranes from the endoplasmic reticulum to the plasma membrane, passing through various cell ...
mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice (eLife Sciences Publications Ltd, 2017-05-23)Energy dissipation through interscapular brown adipose tissue (iBAT) thermogenesis is an important contributor to adaptive energy expenditure. However, it remains unresolved how acute and chronic changes in energy availability ...