Scholarly Works - Institute of Metabolic Science
About this collection
Recent Submissions
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A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits.
(Wiley, 2015-12)Diseases often cooccur in individuals more often than expected by chance, and may be explained by shared underlying genetic etiology. A common approach to genetic overlap analyses is to use summary genome-wide association ... -
A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits.
(Springer Science and Business Media LLC, 2017-02)Shared genetic aetiology may explain the co-occurrence of diseases in individuals more often than expected by chance. On identifying associated variants shared between two traits, one objective is to determine whether such ... -
No metabolic effects of mustard allyl-isothiocyanate compared with placebo in men.
(Elsevier BV, 2017-11)Background: Induction of nonshivering thermogenesis can be used to influence energy balance to prevent or even treat obesity. The pungent component of mustard, allyl-isothiocyanate (AITC), activates the extreme cold receptor ... -
Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats
(Company of Biologists, 2016-10-01)'Developmental programming', which occurs as a consequence of suboptimal in utero and early environments, can be associated with metabolic dysfunction in later life, including an increased incidence of cardiovascular disease ...
