Scholarly Works - Cancer Research UK Cambridge Institute

 

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Recent Submissions

  • Special Issue: Cancer Metabolism 

    Madhu, B (MDPI AG, 2017-08-07)
    Abstract: This special issue is designed to present the latest research findings and developments in the field of cancer metabolism. Cancer is a complex disease and a common term used for more than 100 diseases, whereas ...

  • Emergence and universality in the regulation of stem cell fate 

    Rulands, S; Simons, Benjamin David (Elsevier, 2017-10)
    The mechanisms that control cell fate behaviour during development, and the factors leading to their dysregulation in disease, remain the subject of interest and debate. Lately, advances in single-cell genomics have shifted ...

  • Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature 

    Daste, F; walrant, A; Holst, MR; Gadsby, Jonathan Richard; Mason, J; Lee, Jieun; Brook, D et al.
    The conditional use of actin during clathrin-mediated endocytosis in mammalian cells suggests that the cell controls whether and how actin is used. Using a combination of biochemical reconstitution and mammalian cell ...

  • Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates 

    Moad, M; Hannezo, E; Buczacki, SJ; Wilson, L; El-Sherif, A; Sims, D; Pickard, R et al. (Elsevier, 2017-08-15)
    Sporadic mitochondrial DNA mutations serve as clonal marks providing access to the identity and lineage potential of stem cells within human tissues. By combining quantitative clonal mapping with 3D reconstruction of adult ...

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