Scholarly Works - Cancer Research UK Cambridge Institute
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When comparing biological conditions using mass cytometry data, a key challenge is to identify cellular populations that change in abundance. Here, we present a computational strategy for detecting 'differentially abundant' ...
(Annual Reviews, 2018-04-01)The hallmarks of cancer was an attempt to describe the underlying principles of carcinogenesis. In their latest iteration, there is a particular focus on the role that the microenvironment and signalling between cancer ...
Identification of potential therapeutic targets in prostate cancer through a cross-species approach. (Wiley, 2018-02-05)Genetically engineered mouse models of cancer can be used to filter genome-wide expression datasets generated from human tumours, and identify gene expression alterations that are functionally important to cancer development ...