Scholarly Works - Cancer Research UK Cambridge Institute
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Autophagy is an evolutionary conserved catabolic pathway whose modulation has been linked to diverse disease states, including age-associated disorders. Conventional and conditional whole body knockout mouse models of key ...
Detection of early neoplasia in Barrett's esophagus using lectin-based near-infrared imaging: an ex vivo study on human tissue. (2018-01-17)The incidence of esophageal adenocarcinoma (EAC) has increased dramatically in the Western world over the last 30 years. Despite treatment advances this cancer is still associated with a 5-year survival of less than 15%, ...
Inactivation of the VHL (Von Hippel Lindau) tumour suppressor has long been recognised as necessary for the pathogenesis of clear cell renal cancer (ccRCC); however, the molecular mechanisms underlying transformation and ...