Recent Submissions

  • Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development. 

    Nahorski, Michael Stefan; Borner, Georg HH; Shaikh, Samiha S; Davies, Alexandra; Al-Gazali, Lihadh; Antrobus, Robin; Woods, Christopher Geoffrey (Nature Publishing Group, 2018-02-05)
    The repertoire of cell types in the human nervous system arises through a highly orchestrated process, the complexity of which is still being discovered. Here, we present evidence that CHC22 has a non-redundant role in an ...
  • Ubiquitin E3 ligase mediated regulation of HMG-CoA Reductase 

    Menzies, Sam (2018-05-19)
    Loss-of-function genetic screens are a powerful approach to identify the genes involved in biological processes. For nearly a century, forward genetic screens in model organisms have provided enormous insight into many ...
  • Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags. 

    O'Brien, Jonathon J; O'Connell, Jeremy D; Paulo, Joao A; Thakurta, Sanjukta; Rose, Christopher M; Weekes, Michael Paul; Huttlin, Edward L et al. (American Chemical Society, 2018-01)
    Mass spectrometry (MS) has become an accessible tool for whole proteome quantitation with the ability to characterize protein expression across thousands of proteins within a single experiment. A subset of MS quantification ...
  • The Human Cell Atlas. 

    Regev, Aviv; Teichmann, Sarah A; Lander, Eric S; Amit, Ido; Benoist, Christophe; Birney, Ewan; Bodenmiller, Bernd et al. (2017-12-05)

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