Cambridge Institute for Medical Research

NBEAL2 is required for neutrophil and NK cell function and pathogen defense.

Sowerby, John M; Thomas, David C; Clare, Simon; Espéli, Marion; Guerrero, Jose A; Hoenderdos, Kim; Harcourt, KatherineMarsden, MorganAbdul-Karim, JuneidClement, MathewAntrobus, RobinUmrania, YagneshBarton, Philippa RFlint, Shaun MJuss, Jatinder KCondliffe, Alison MLyons, Paul AHumphreys, Ian RChilvers, Edwin ROuwehand, Willem HDougan, GordonSmith, Kenneth Gc et al. (American Society for Clinical Investigation, 2017-08-07)
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors

Huntly, BJP; laurenti, E; Horton, SJ; Hodson, D (Nature Publishing Group, 2017-09-01)
Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity

Gottgens, B
MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics

Masters, TA; Tumbarello, DA; Chibalina, MV; Buss, F (Elsevier, 2017-06)

APPL1- and RAB5-positive signaling endosomes play a crucial role in the activation of AKT in response to extracellular stimuli. Myosin VI (MYO6) and two of its cargo adaptor proteins, GIPC and TOM1/TOM1L2, localize to these ...