About this collection

Recent Submissions

  • Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23 

    Lee, JYW; Hsu, C-K; Michael, M; Nanda, A; Liu, L; McMillan, JR; Pourreyron, C et al. (Elsevier (Cell Press), 2017-02-02)
    SPG23 is an autosomal-recessive neurodegenerative subtype of lower limb spastic paraparesis with additional diffuse skin and hair dyspigmentation at birth followed by further patchy pigment loss during childhood. Previously, ...
  • Myosin VI facilitates connexin 43 gap junction accretion 

    Waxse, BJ; Sengupta, P; Hesketh, GG; Lippincott-Schwartz, J; Buss, F (The Company of Biologists, 2017-03-01)
    In this study, we demonstrate myosin VI enrichment at Cx43 (also known as GJA1)-containing gap junctions (GJs) in heart tissue, primary cardiomyocytes and cell culture models. In primary cardiac tissue and in fibroblasts ...
  • Filopodia formation and endosome clustering induced by mutant plus-end-directed myosin VI. 

    Masters, TA; Buss, F (National Academy of Sciences, 2017-02-14)
    Myosin VI (MYO6) is the only myosin known to move toward the minus end of actin filaments. It has roles in numerous cellular processes, including maintenance of stereocilia structure, endocytosis, and autophagosome maturation. ...
  • An Automated Image Analysis System to Quantify Endosomal Tubulation. 

    Newton, TM; Reid, E
    Recycling of cargos from early endosomes requires regulation of endosomal tubule formation and fission. This regulation is disrupted in cells depleted of the microtubule severing enzyme spastin, causing elongation of ...

View more