Scholarly Works - Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute
About this collection
Recent Submissions
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Comparative omics and feeding manipulations in chicken indicate a shift of the endocrine role of visceral fat towards reproduction.
(Springer nature, 2018-04-26)BACKGROUND: The mammalian adipose tissue plays a central role in energy-balance control, whereas the avian visceral fat hardly expresses leptin, the key adipokine in mammals. Therefore, to assess the endocrine role of ... -
Direct Conversion of Mouse Fibroblasts into Cholangiocyte Progenitor Cells
(Elsevier, 2018-05-08)Disorders of the biliary epithelium, known as cholangiopathies, cause severe and irreversible liver diseases. The limited accessibility of bile duct precludes modeling of several cholangiocyte-mediated diseases. Therefore, ... -
Ultrashort Echo Time Imaging of the Osteochondral Junction in Subjects with Knee Osteoarthritis and Age-matched Healthy Volunteers
SYNOPSIS We describe in vivo translation of ultrashort TE (UTE) imaging of the osteochondral junction (OCJ) at the knee in 9 subjects with osteoarthritis (OA) and 4 age-matched healthy volunteers. The OCJ plays an important ... -
Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.
(The Company of Biologists, 2016-07-15)New hair follicles (HFs) do not form in adult mammalian skin unless epidermal Wnt signalling is activated genetically or within large wounds. To understand the postnatal loss of hair forming ability we monitored HF formation ...
