MRC Cancer Unit
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Introduction Oesophageal adenocarcinoma (OAC) remains a poor prognosis cancer type. The pre-malignant lesion for this type of cancer is called Barrett’s Oesophagus (BO), which has two subtypes, Gastric Metaplasia (GM) ...
An Investigation of Mutational Signatures in the Evolution of Oesophageal adenocarcinoma Sujath Abbas Oesophageal adenocarcinoma (OAC) remains a public health challenge with dismal survival rates and increasing incidence. ...
Tumourigenesis occurs when a series of genome alterations occur in the same group of cells and cause uncontrolled cell proliferation. Therefore, to understand the journey from healthy to cancerous tissue, it is important ...