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dc.contributor.authorWestwater, Margaret L
dc.contributor.authorFletcher, Paul C
dc.contributor.authorZiauddeen, Hisham
dc.date.accessioned2016-06-20T12:45:28Z
dc.date.available2016-06-20T12:45:28Z
dc.date.issued2016-11
dc.identifier.issn1436-6207
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/256387
dc.description.abstractPURPOSE: As obesity rates continue to climb, the notion that overconsumption reflects an underlying 'food addiction' (FA) has become increasingly influential. An increasingly popular theory is that sugar acts as an addictive agent, eliciting neurobiological changes similar to those seen in drug addiction. In this paper, we review the evidence in support of sugar addiction. METHODS: We reviewed the literature on food and sugar addiction and considered the evidence suggesting the addictiveness of highly processed foods, particularly those with high sugar content. We then examined the addictive potential of sugar by contrasting evidence from the animal and human neuroscience literature on drug and sugar addiction. RESULTS: We find little evidence to support sugar addiction in humans, and findings from the animal literature suggest that addiction-like behaviours, such as bingeing, occur only in the context of intermittent access to sugar. These behaviours likely arise from intermittent access to sweet tasting or highly palatable foods, not the neurochemical effects of sugar. CONCLUSION: Given the lack of evidence supporting it, we argue against a premature incorporation of sugar addiction into the scientific literature and public policy recommendations.
dc.description.sponsorshipWellcome Trust (Senior Fellowship award)
dc.languageEnglish
dc.language.isoen
dc.publisherSpringer Science and Business Media LLC
dc.rightsAttribution 4.0 International
dc.rightsAttribution 4.0 International
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAnimal neuroscience
dc.subjectBinge eating
dc.subjectDrug addiction
dc.subjectObesity
dc.subjectSugar addiction
dc.subjectAnimals
dc.subjectBehavior, Addictive
dc.subjectBinge-Eating Disorder
dc.subjectDietary Fats
dc.subjectDietary Sucrose
dc.subjectDisease Models, Animal
dc.subjectFood
dc.subjectGlycemic Index
dc.subjectGlycemic Load
dc.subjectHumans
dc.subjectMotivation
dc.subjectObesity
dc.subjectReceptors, Dopamine D2
dc.subjectSubstance-Related Disorders
dc.titleSugar addiction: the state of the science.
dc.typeArticle
dc.description.versionThis is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s00394-016-1229-6
prism.endingPage69
prism.publicationDate2016
prism.publicationNameEur J Nutr
prism.startingPage55
prism.volume55
dc.identifier.doi10.17863/CAM.330
dcterms.dateAccepted2016-05-20
rioxxterms.versionofrecord10.1007/s00394-016-1229-6
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.licenseref.startdate2016-07-02
dc.contributor.orcidWestwater-Wozniak, Margaret [0000-0002-2918-0979]
dc.contributor.orcidFletcher, Paul [0000-0001-8257-1517]
dc.contributor.orcidZiauddeen, Hisham [0000-0003-4044-1719]
dc.identifier.eissn1436-6215
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (093875/Z/10/Z)
pubs.funder-project-idMedical Research Council (MC_UU_12012/5)
cam.issuedOnline2016-07-02


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International