Tracking the embryonic stem cell transition from ground state pluripotency
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Mouse embryonic stem (ES) cells are locked into self-renewal by shielding from inductive cues. Release from this ground state in minimal conditions offers a system for delineating developmental progression from naive pluripotency. Here we examined the initial transition process. The ES cell population behaves asynchronously. We therefore exploited a short-half-life
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1477-9129
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MRC (G1100526)
Wellcome Trust (091484/Z/10/Z)
Biotechnology and Biological Sciences Research Council (BB/M004023/1)