MRC Laboratory of Molecular Biology
Recent Submissions
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The Life of Prion: an investigation into the physiological role of a prion-like protein in the nematode Caenorhabditis elegans
For centuries, the threat of prion disease has plagued populations – whether it be in the form of scrapie ravaging through the sheep populations of Spain in the eighteenth century, fatal familial insomnia afflicting families ... -
Mechanisms of multipass membrane protein biogenesis
(2020-07-30)A crucial aspect of cellular physiology is the ability of a single cell to remain autonomous and concentrate reagents to improve efficiency. Semi-permeable membranes facilitate autonomy via an outer barrier (plasma membrane) ... -
How codon choice determines evolvability and evolutionary robustness in short linear motifs
(2020-10-24)Short linear motifs, made up of 2-10 amino acids in linear sequence space, are a central component of cellular decision making through proteins. They form a modular system in cells where combinations of domains and motifs ... -
Spatial-memory control of defensive actions
(2020-10-24)Adapting anti-predatory defensive strategies to the properties of the environment is critical for survival. Here, I investigated the dependence of mouse instinctive defensive behaviours on memory of the spatial environment, ...
