Theses - MRC Laboratory of Molecular Biology
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Recent Submissions
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Identification and Evolution of New Orthogonal Aminoacyl-tRNA Synthetase/tRNA Pairs for Genetic Code Expansion
Genetic code expansion is the branch of molecular biology aiming to expand the repertoire of amino acids which can be incorporated into proteins in vivo. A central challenge in expanding the genetic code of cells to ... -
The organisation of a third-order olfactory brain region in the vinegar fly
Neural representations of the chemosensory world generate both learned and instinctive behaviours. Olfactory systems detect a huge range of volatiles by combining patterns of activity across input channels. The lateral ... -
Synthetic In Vivo Reconstitution of Asymmetric Cell Division
Asymmetric cell division (ACD) is the process whereby one dividing cell gives rise to two daughter cells of differing fates. ACD is known to be controlled, at least in part, by protein complexes that reside asymmetrically ... -
The role of IFN-γ in cell-autonomous immune responses against Salmonella Typhimurium and Toxoplasma gondii
The research presented in this thesis investigates the function of interferon gamma in vacuoles, namely Salmonella enterica serovar Typhimurium and Toxoplasma gondii. IFN-γ is a cytokine that functions in both the innate ...
