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Recent Submissions

  • Structure and Function of the ER-Membrane Complex 

    Phillips, Ben (2020-06-17)
    The ER-Membrane Complex (EMC) is a highly conserved heterodecameric membrane protein complex, found in the Endoplasmic Reticulum (ER) across almost all branches of eukaryotic life. The EMC has been implicated in a wide ...
  • Studies of PARP-1 activation and inhibition using NMR spectroscopy 

    Ogden, Tom
    Poly(ADP-ribose)polymerase 1 (PARP-1) is a highly abundant multi-domain chromatin-associated enzyme found in all higher eukaryotic cell nuclei. It is the founding member of the PARP family of enzymes that modify themselves ...
  • Genetic dissection of circuits underlying the modular structure of the Superior Colliculus 

    Masullo, Laura (2020-05-16)
    In order to successfully interact with the environment, animals need to produce accurate movements towards specific positions in space. A crucial region of the brain that guides such goal-oriented movements is the superior ...
  • Circadian Orchestration of the Cellular Proteome 

    Wong, David Chuen Soong (2020-01-31)
    Circadian rhythms are biological oscillations with a period length of roughly 24 hours. They confer an adaptive advantage as they enable the prediction of the regular environmental changes caused by the rotation of the ...

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