Experimental Medicine and Immunotherapeutics (EMIT)

Recent Submissions

  • THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview. 

    Alexander, Stephen Ph; Kelly, Eamonn; Marrion, Neil V; Peters, John A; Faccenda, Elena; Harding, Simon D; Pawson, Adam J et al. (Wiley-Blackwell, 2017-12)
    The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective ...

  • THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors. 

    Alexander, Stephen Ph; Christopoulos, Arthur; Davenport, Anthony P; Kelly, Eamonn; Marrion, Neil V; Peters, John A; Faccenda, Elena et al. (Wiley-Blackwell, 2017-12)
    The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access ...

  • [Pyr¹]Apelin-13(₁-₁₂) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr¹]Apelin-13 

    Yang, P; Kuc, RE; Brame, AL; Dyson, A; Singer, M; Glen, RC; Cheriyan, J et al. (Frontiers Media, 2017-02-28)
    Aims: Apelin is a predicted substrate for ACE2, a novel therapeutic target. Our aim was to demonstrate the endogenous presence of the putative ACE2 product [Pyr(1)]apelin-13(1-12) in human cardiovascular tissues and to ...

  • Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor 

    Maguire, JJ; Kirby, HR; Mead, EJ; Kuc, RE; d'Anglemont de Tassigny, X; Colledge, WH; Davenport, AP (PLoS, 2011-11-22)
    Kisspeptins, the ligands of the kisspeptin receptor known for its roles in reproduction and cancer, are also vasoconstrictor peptides in atherosclerosis-prone human aorta and coronary artery. The aim of this study was to ...

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